Thiophosgene, chemically known as Thiocarbonyl dichloride or Dichloromethanethione, is a pivotal chemical compound with the formula CCl2S (or CSCl2). This brown-red fuming liquid, identified by its CAS No. 463-71-8, holds immense significance in various industrial applications, particularly as a versatile intermediate in complex organic syntheses. Its unique molecular structure, featuring two reactive C–Cl bonds, makes it an indispensable building block for creating a wide array of specialized chemicals. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of high-quality Thiophosgene, adhering to stringent purity standards to meet the diverse needs of the global chemical industry.

Thiophosgene exhibits distinct physical and chemical properties that underline its utility and handling requirements. It has a molecular weight of 114.98 g/mol and a density of approximately 1.6±0.1 g/cm3. The compound boasts a boiling point around 73.0±9.0 °C at 760 mmHg and a refractive index of 1.564. Notably, its flash point is -2.0±18.7 °C, indicating its volatile nature and the need for careful handling. Our product consistently achieves an assay of ≥95%, with typical results demonstrating purity levels of 98.5%, confirming its qualification according to rigorous specifications.

One of the primary applications of Thiophosgene lies in the agricultural sector. It serves as an essential intermediate for the preparation of various agrochemicals, contributing significantly to modern farming practices. For instance, Thiophosgene is critical in the synthesis of the acaricide butyl ether urea, a compound vital for controlling mites in crops. Furthermore, it is a crucial precursor for developing thiourethane insecticides and a range of herbicides, playing a direct role in crop protection and yield enhancement. Its versatility also extends to being an intermediate in the production of Diafenthiuron, a prominent agricultural fungicide and insecticide.

Beyond agrochemicals, Thiophosgene is highly valued in general organic synthesis. It is extensively used to prepare compounds with the connectivity CSX2, where X can be an alkoxide (OR) or an amine (NHR), facilitating the formation of complex structures. The compound is also instrumental in converting primary amines into isothiocyanates, a reaction with broad applications in medicinal chemistry and material science. Moreover, Thiophosgene acts as a dienophile in certain reactions, leading to the formation of 5-thiacyclohexene derivatives. It is famously recognized as the appropriate reagent in the Corey-Winter synthesis, a stereospecific method for converting 1,2-diols into alkenes, showcasing its precision in creating specific molecular arrangements.

Given its nature as a highly toxic substance with a persistent, choking odor, proper handling and storage of Thiophosgene are paramount. Inhalation can cause severe irritation, burns, and potentially fatal delayed pulmonary edema. It is classified under Hazard Class 6.1 and Packing Level Class I, with UN No. 2474. For optimal safety and preservation of quality, Thiophosgene should be stored in a cool, well-ventilated warehouse, kept strictly away from sources of fire and heat, with temperatures not exceeding 37 °C. NINGBO INNO PHARMCHEM CO.,LTD., a reputable manufacturer and supplier, ensures that all our products are packaged securely, typically in 25 kg barrels, with customizable packaging options available to meet specific customer requirements.

As a leading manufacturer and supplier of Thiophosgene, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality products to buyers worldwide. Our robust production processes and stringent quality control ensure consistent product integrity. For those looking to buy or purchase Thiophosgene, we offer competitive prices and reliable delivery services. We encourage potential customers and distributors to connect with us for detailed product information, technical specifications, and competitive quotations. Partner with us for your Thiophosgene needs and experience the assurance of a dependable supply chain from a trusted industry leader.