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Trandolapril (CAS 87679-37-6): Applications in Cardiovascular Medicine

Trandolapril, identified by CAS number 87679-37-6, is a critical pharmaceutical compound valued for its potent Angiotensin-Converting Enzyme (ACE) inhibitory activity. Its unique pharmacological profile, characterized by high lipophilicity and prolonged efficacy, makes it a cornerstone in managing cardiovascular conditions. This article delves into the primary applications of Trandolapril and highlights why sourcing from a reputable manufacturer is essential for pharmaceutical developers.

Therapeutic Applications of Trandolapril

The principal uses of Trandolapril revolve around its effectiveness in regulating blood pressure and supporting cardiac health:

  • Hypertension Management: As an ACE inhibitor, Trandolapril works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This leads to vasodilation and a reduction in blood pressure, making it an invaluable tool for treating essential hypertension. Pharmaceutical companies looking to formulate effective antihypertensive drugs can purchase Trandolapril as a key active pharmaceutical ingredient (API) or intermediate.
  • Post-Myocardial Infarction (Heart Attack) Recovery: Studies have indicated that Trandolapril can improve survival rates and reduce the incidence of heart failure following a myocardial infarction. This application underscores its importance in cardiac care and the need for a consistent, high-quality supply chain.
  • Other Cardiovascular Conditions: While primarily used for hypertension and post-MI recovery, Trandolapril is also explored for its potential benefits in other related cardiovascular diseases, making it a subject of ongoing research and development.

Quality and Sourcing Considerations for Pharmaceutical Professionals

When you buy Trandolapril for pharmaceutical applications, quality is non-negotiable. The compound typically appears as a white powder, with a purity level of ≥99% being a standard requirement. Its molecular formula is C24H34N2O5, and its molecular weight is 430.54. Sourcing from a reliable supplier, especially a manufacturer in China, can offer competitive advantages in terms of cost and volume. It is vital to partner with suppliers who can provide detailed technical documentation, including CAS number 87679-37-6 verification, and adhere to stringent manufacturing practices.

Choosing the Right Partner

Selecting the right Trandolapril supplier ensures the integrity and efficacy of the final drug product. Factors such as consistent batch quality, efficient logistics (ocean, land, air), and flexible payment options contribute to a seamless procurement process. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing high-grade Trandolapril, supporting the pharmaceutical industry's need for reliable and quality-assured intermediates. Inquire about Trandolapril price and availability to facilitate your drug development projects.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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