Tretinoin Powder, also widely recognized as Retinoic Acid, with the chemical designation CAS 302-79-4, stands as a pivotal raw material in both the pharmaceutical and cosmetic industries. This compound is an intermediate metabolite of Vitamin A, playing a crucial role in various biological processes, particularly those involving cell growth, differentiation, and proliferation.

As a finely produced yellow to orange powder, Tretinoin exhibits specific solubility characteristics. It is known to dissolve readily in organic solvents such as carbinol and ethanol, and is also soluble in vegetable oils and lipids. However, its stability is highly sensitive to environmental factors. Tretinoin is inherently unstable when exposed to light and heat, and it can easily absorb moisture, leading to degradation. Proper storage in a cool, dry place, protected from light and heat, is therefore essential to maintain its purity and efficacy over its two-year shelf life.

The applications of Tretinoin Powder are extensive and well-documented. In the pharmaceutical sector, it is a primary active ingredient for the treatment of a variety of dermatological conditions. This includes common ailments such as acne vulgaris, particularly those with comedo skin lesions, where its ability to promote cell turnover and prevent follicular blockage is highly effective. Beyond acne, Tretinoin is also used in the management of more severe skin disorders, including psoriasis, ichthyosis, lichen planus, pityriasis rubra, and follicular keratosis. Its mechanism of action involves binding to specific retinoic acid receptors (RARs), which in turn modulates gene expression, influencing cellular differentiation and keratinization. Furthermore, Tretinoin has shown efficacy in treating acute promyelocytic leukemia (APL), demonstrating its systemic therapeutic potential when formulated appropriately.

In the cosmetic industry, Tretinoin Powder is highly valued for its powerful anti-aging and skin rejuvenation properties. It is incorporated into various formulations designed to address signs of aging, such as fine lines and wrinkles. By stimulating collagen production and increasing epidermal cell turnover, Tretinoin helps to improve skin texture, reduce roughness, and enhance overall complexion, often resulting in a ruddier, more youthful appearance. It is also effective in treating hyperpigmentation and improving skin elasticity. Its ability to unclog pores and reduce inflammation makes it a potent ingredient in products targeting oily skin and associated issues like blackheads.

The versatility of Tretinoin Powder as a raw material necessitates stringent quality control during its production. High-purity grades, typically exceeding 99%, are required, especially for pharmaceutical applications. Adherence to internationally recognized standards such as USP, BP, GMP, ISO 9001, and others is crucial to ensure the safety and efficacy of downstream products. Testing methods like HPLC are employed to verify purity and quality. Manufacturers specializing in this compound often provide documentation such as Certificates of Analysis (COA) to confirm product specifications.

Reliable sourcing and efficient supply chain management are paramount when dealing with sensitive raw materials like Tretinoin Powder. Producers must have the capacity for consistent manufacturing and timely delivery. Packaging standards, such as the use of foil bags, drums, or cartons depending on quantity (e.g., 1kg bags, 25kg drums), are designed to protect the product during transit and storage. Flexibility in shipping methods, including international express, air freight, and sea freight, allows suppliers to meet diverse customer needs globally.

For companies looking to develop pharmaceutical formulations or advanced cosmetic products, sourcing high-quality Tretinoin Powder (Retinoic Acid) CAS 302-79-4 is a critical step. Establishing a partnership with a reputable manufacturer is key to ensuring a consistent supply of material that meets the required purity and regulatory standards. Whether you are a formulator seeking raw ingredients for topical creams, gels, or other applications, or a researcher exploring new therapeutic uses, understanding the properties and quality requirements of Tretinoin Powder is essential.

Those interested in exploring the potential of this versatile raw material or seeking a reliable source for their production needs are encouraged to investigate supply options. Details regarding Tretinoin powder manufacturer capabilities, Retinoic acid supplier profiles, Tretinoin powder price structures, and options to buy Retinoic acid powder or purchase CAS 302-79-4 in bulk quantities can be found by contacting specialized chemical suppliers. Engaging with experienced providers ensures access to not only the product but also necessary technical support and quality documentation. Securing a competitive Tretinoin powder wholesale price is often achievable through direct engagement with manufacturers or major distributors who understand the nuances of handling and supplying this sensitive, yet valuable, compound.
Written by NINGBO INNO PHARMCHEM CO.,LTD.