Trifluoromethanesulfonic acid, commonly known as Triflic acid, is a highly versatile and potent organic acid with the Chemical Abstracts Service (CAS) number 1493-13-6. It is also referred to by synonyms such as TFMS, TFSA, HOTf, or TfOH. This colorless, transparent liquid stands out in the chemical industry as one of the strongest known organic acids, belonging to the class of superacids. Its exceptional properties make it an indispensable reagent across a multitude of applications, driving innovation in various sectors.
At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing high-quality Trifluoromethanesulfonic acid with an assay of 99.5% minimum. The molecular formula for this compound is CHF3O3S, and it has a molecular weight of 150.08 g/mol. Its distinctive physical characteristics include a boiling point of 162 °C, a melting point of -40 °C, and a density of approximately 1.71 g/cm3 at 20 °C. The acidity is notably strong, with a pH value around 0.11 in water, signifying its almost complete dissociation. Furthermore, Triflic acid exhibits remarkable stability against oxidation and reduction, making it a reliable and powerful tool in demanding chemical environments.
The applications of Trifluoromethanesulfonic acid are incredibly diverse due to its strong acidity and catalytic efficiency. It serves as a superior catalyst for a wide array of organic synthesis reactions, including alkylation, esterification, etherification, acylation, isomerization, ethoxylation, cyclization, and cationic rearrangement. Its potency also makes it an excellent choice for cationic polymerization reactions, particularly in the plastics industry. In pharmaceutical synthesis, Triflic acid is invaluable for the preparation of complex molecules such as nucleosides, antibiotics, steroids, proteins, glycosides, and vitamins. It is also utilized in silicone rubber modification and plays a role in the synthesis of herbicides and growth regulators, as well as in the sugar industry. Beyond chemical synthesis, the triflate anion, derived from Triflic acid, is widely recognized as an outstanding leaving group, enhancing reactivity in many organic transformations, and proving to be an excellent anion for ionic liquids. Its utility extends to electronic applications, including liquid crystals and batteries.
Given its strong corrosive and hygroscopic nature, proper handling and storage of Trifluoromethanesulfonic acid are paramount. It should always be kept in a well-closed, light-resistant, dry, and cool place to maintain its purity and prevent degradation. For safety, it is imperative to wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles or full-face shields, lab coats or acid-resistant aprons, and closed-toe shoes. All operations involving Triflic acid should be conducted in a chemical fume hood to prevent inhalation of corrosive vapors. When diluting, always remember to add acid to water slowly, never the reverse, to prevent dangerous exothermic reactions. Store acids in clearly labeled, corrosion-resistant containers, segregated from bases, organic solvents, and oxidizers. In case of skin or eye contact, flush immediately with plenty of water for at least 15 minutes and seek medical attention. Spills should be managed by trained personnel using appropriate neutralizing agents. Disposal of this powerful chemical must always be conducted through a certified hazardous waste disposal company, adhering to all local, national, and international regulations.
As a leading manufacturer and reliable supplier of Trifluoromethanesulfonic acid (CAS 1493-13-6), NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering products of the highest quality, accompanied by comprehensive certificates and reports to ensure full assurance. Samples are available upon request for your evaluation. For detailed product documentation, competitive price, and to learn more about how to buy or purchase this essential chemical for your specific needs, please do not hesitate to contact us to get quotes now. Our team is ready to assist you with inquiries and facilitate your order, ensuring a seamless experience for acquiring premium chemical solutions.
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