Trimesoyl Chloride (TMC), identified by CAS Number 4422-95-1, is a pivotal organic compound known for its versatile applications across numerous industrial sectors. Also recognized by synonyms such as 1,3,5-Benzenetricarbonyl trichloride, Trimesic acid trichloride, and 1,3,5-Benzenetricarboxylic acid chloride, TMC is characterized by its molecular formula C9H3Cl3O3 and a molecular weight of 265.48 g/mol. It typically appears as a white to pale yellow solid, transforming into a clear yellow liquid upon melting.

One of the most significant applications of Trimesoyl Chloride lies in the realm of membrane technology. It is an indispensable component in the production of high-performance thin-film composite (TFC) membranes, particularly those utilized for reverse osmosis. These membranes are critical for processes such as seawater desalination, high-purity water purification, and advanced gas separation. TMC's unique chemical structure facilitates crucial interfacial polymerization reactions, forming dense yet permeable selective layers that are essential for efficient filtration and separation processes. Its ability to create robust and highly selective barriers is central to enhancing membrane performance and longevity.

Beyond membrane technology, TMC serves as a vital building block in the synthesis of various advanced materials and polymers. It is frequently employed in the manufacturing of cellulose-based materials, including specialized microcapsules, where it significantly enhances water permeability. As a key polymer raw material, Trimesoyl Chloride also finds use in the creation of complex chemical structures, such as chiral azoaromatic dendrimeric systems, showcasing its role in cutting-edge material science. Its reactive acid chloride groups enable the formation of strong bonds, leading to materials with desired mechanical and chemical properties.

The utility of Trimesoyl Chloride extends into environmental applications, particularly in wastewater treatment and water purification systems. Its antioxidative properties prove beneficial in breaking down persistent organic compounds, including chlorinated hydrocarbons, thereby aiding in the detoxification of industrial effluents. Furthermore, TMC's properties allow it to facilitate the transport of ionic species across membranes, contributing to more effective contaminant removal and resource recovery in diverse water treatment scenarios.

Emerging research also highlights the potential of Trimesoyl Chloride in biomedical fields. Studies have explored its selective uptake by bladder cancer cells, suggesting possibilities for targeted therapies or diagnostic tools. Additionally, its role in enhancing the selectivity and interfacial properties of nanocomposites for drug delivery systems has been investigated, particularly in the context of diabetes treatment. These exploratory applications underscore TMC's broad potential beyond conventional industrial uses.

From a chemical perspective, Trimesoyl Chloride exhibits a melting point typically ranging from 32 to 36.3 °C and a boiling point between 175-181 °C at reduced pressure. Its density is approximately 1.487 g/mL at 25 °C. While it decomposes in water, its unique characteristics, particularly in membrane applications, allow for excellent water permeability despite being insoluble. The compound is known for its stability under normal temperatures and pressures, ensuring reliable performance in various synthetic and industrial processes. High purity levels, typically above 98%, are consistently maintained to meet stringent industry standards.

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