Trimetazidine Dihydrochloride, often abbreviated as TMDH, stands as a pivotal active pharmaceutical ingredient (API) in cardiovascular medicine. Known for its distinct anti-ischemic properties, this compound offers a significant therapeutic approach, particularly in the management of angina pectoris. As a leading chemical supplier, we are committed to providing high-quality TMDH, ensuring its efficacy and safety for pharmaceutical applications worldwide.

What sets Trimetazidine Dihydrochloride apart is its unique cellular protective mechanism. It is recognized as the first anti-ischemic agent designed to protect cells from the damaging effects of ischemia. The compound primarily achieves this by inhibiting fatty acid metabolism, thereby shifting myocardial energy production towards glucose utilization. This metabolic reorientation is crucial for maintaining cellular integrity and function under ischemic conditions, ultimately alleviating the symptoms associated with angina. Its ability to improve the efficiency of myocardial energy metabolism makes it an invaluable asset in cardiac care.

Chemically, Trimetazidine Dihydrochloride has the molecular formula C14H24Cl2N2O3 and a molecular weight of 339.25800. It is also known by its synonyms such as 1-(2,3,4-TriMethoxybenzyl)piperazine Dihydrochloride. Physically, it presents as a white or off-white crystalline powder, characterized by its solid form. Key physical properties include a melting point typically ranging from 231 to 235 °C and a boiling point around 364 °C at 760 mmHg. Furthermore, its flash point is observed at 174 °C, with a vapor pressure of 1.73E-05mmHg at 25°C, affirming its stability and handling characteristics.

Ensuring the highest standards of quality is paramount for any pharmaceutical raw material. Our Trimetazidine Dihydrochloride undergoes rigorous quality control checks to guarantee superior purity and consistency. Each batch is meticulously tested against stringent specifications. For instance, the appearance is consistently an off-white crystalline powder, and solutions are confirmed to be clear or with minimal turbidity, well within acceptable limits. Acidity, loss on drying, and total impurity levels are diligently monitored and maintained, significantly below the maximum allowable thresholds. With a typical content of over 99%, and the largest single impurity often undetectable, our product consistently meets and often exceeds pharmaceutical grade requirements, providing a reliable and safe component for drug formulations. This commitment to quality ensures that our Trimetazidine Dihydrochloride is truly up to standard and suitable for critical medical applications.

The primary application of Trimetazidine Dihydrochloride is its use in anti-angina drugs, offering symptomatic relief and myocardial protection for patients suffering from coronary artery disease. Its role in improving cardiac energy metabolism is well-established, making it a cornerstone in therapeutic regimens. For pharmaceutical companies and research institutions seeking a dependable Trimetazidine Dihydrochloride manufacturer or supplier, we offer a consistent and high-quality product. We understand the critical importance of a robust supply chain for APIs. For details on Trimetazidine Dihydrochloride price and to buy Trimetazidine Dihydrochloride or to purchase Trimetazidine Dihydrochloride in bulk, please reach out to our sales team. We are dedicated to facilitating seamless transactions and providing comprehensive support for your procurement needs.