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Trimethylsulfoxonium Chloride (CAS 5034-06-0): A Key Reagent for Modern Synthesis

NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight a cornerstone product in our fine chemical portfolio: Trimethylsulfoxonium Chloride (TMSOCl), CAS No. 5034-06-0. This highly stable, white to off-white crystalline powder is a critical reagent in the world of organic synthesis, enabling chemists to build complex molecules with precision and efficiency.

With a molecular formula of $C_3H_9ClOS$ and a molecular weight of 128.62 g/mol, Trimethylsulfoxonium Chloride is renowned for its role in the Corey-Chaykovsky reaction. In this process, it serves as a precursor for the in situ generation of dimethyloxosulfonium methylide. This ylide is an invaluable tool for chemists, allowing for the straightforward synthesis of epoxides, cyclopropanes, and aziridines from aldehydes, ketones, and imines, respectively. These structural motifs are fundamental building blocks in a vast array of biologically active compounds.

Key Properties and Advantages:
Our Trimethylsulfoxonium Chloride is produced to meet stringent quality standards, ensuring a purity of ≥98.0%. Key physical properties include:

  • Appearance: White to off-white crystalline powder
  • Melting Point: 218-222°C (with decomposition)
  • Solubility: Excellent solubility in water and polar organic solvents like DMSO.

Compared to other methylating agents, TMSOCl offers significant advantages. Its solid, crystalline nature makes it easier and safer to handle and store than many alternatives. The reactions involving TMSOCl are often performed under mild conditions, which preserves sensitive functional groups within the target molecule. This controlled reactivity and stereoselectivity make it an indispensable tool in the synthesis pathways for pharmaceuticals, advanced agrochemicals, and specialty materials.

Applications Across Industries:
The versatility of Trimethylsulfoxonium Chloride makes it a high-demand intermediate. In the pharmaceutical industry, it is instrumental in constructing the core structures of new drug candidates. In the agrochemical sector, it facilitates the production of more effective and environmentally benign pesticides and herbicides. Its application extends into material science, where it can be used to modify polymers or create novel functional materials.

As a leading manufacturer and supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing a reliable supply of high-purity Trimethylsulfoxonium Chloride. We understand the critical role that starting material quality plays in the success of our clients' research and production. We offer this product at a competitive price, ensuring our partners receive the best value without compromising on quality. For those looking to buy or purchase Trimethylsulfoxonium Chloride for their synthesis needs, our team is ready to provide comprehensive support and ensure a seamless procurement process. We are your trusted source for this essential chemical reagent.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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