Triphenylsilane (CAS: 789-25-3): A Versatile Reagent for Advanced Chemical Synthesis

Triphenylsilane, identified by its CAS number 789-25-3, is a highly valuable organosilicon compound renowned for its broad utility as a reactant and reagent in modern organic chemistry and catalysis. This compound, with its distinctive triphenylsilyl group, plays a pivotal role in facilitating complex reactions and synthesizing novel materials, making it indispensable for researchers and industries pushing the boundaries of chemical innovation.

The molecular structure of Triphenylsilane is defined by the formula C18H16Si, contributing to a molecular weight of 260.41 g/mol. It typically presents as a white powder, reflecting its high purity. Key physical properties include a melting point ranging from 43 to 45 °C. Its boiling point is notably dependent on pressure, measured at approximately 152 °C at 2 mmHg, or significantly higher, around 347 °C, at standard atmospheric pressure (760 mmHg). The flash point is approximately 76 °C (169 °F), indicating it requires careful handling. For optimal stability and to prevent degradation, Triphenylsilane is best stored under an inert atmosphere, such as nitrogen, at temperatures between 2-8 °C, as it is sensitive to air and moisture, decomposing in water but soluble in methanol.

The applications of Triphenylsilane are remarkably diverse, underscoring its versatility in synthetic methodologies. It acts as a crucial reagent in catalytic hydrogen deuterium exchange reactions of silanes, a process vital for isotopic labeling and mechanistic studies. Furthermore, it is implicated in oxidation reactions, notably by carbon nanotube-gold nanohybrids, showcasing its compatibility with advanced nanomaterials. Its utility extends to hydrolysis reactions mediated by ruthenium complexes, highlighting its role in complex catalytic cycles.

In the realm of organic synthesis, Triphenylsilane is frequently employed in hydrosilylation reactions to produce enolsilanes, which are valuable intermediates in the synthesis of various organic compounds. It also serves as a key precursor for the synthesis of bromosilanes. Beyond these, Triphenylsilane facilitates the ozone oxidation of silyl-alkenes, leading to the intriguing synthesis of α-O-silylated acyloin derivatives. It is also an essential component in the synthesis of specialized metallic complexes, such as hydrido silyl and bis(silyl) bis(imidazolinylidene) nickel complexes, which find applications in diverse catalytic systems.

Recent advancements have further expanded its application profile. Triphenylsilane contributes to the hydrotrifluoromethylation of various alkenes, including styrenes, unactivated alkenes, acrylates, acrylamides, and vinyl-heteroatom-substituted alkenes, under photoredox catalysis conditions. This method provides a powerful tool for incorporating trifluoromethyl groups into organic molecules. Moreover, it is central to innovative cooperative catalysis involving copper and nickel catalysts, enabling the stereospecific hydroalkylation of terminal alkynes with alkyl iodides, yielding E-alkenes with excellent anti-Markovnikov selectivity. These cutting-edge applications solidify Triphenylsilane's status as a foundational component in advanced chemical research and industrial processes.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to being a premier manufacturer and supplier of high-quality Triphenylsilane (CAS: 789-25-3). Our production processes adhere to stringent quality control standards, ensuring that every batch meets the highest purity specifications required for sensitive chemical applications. We understand the critical importance of reliable and consistent supply in the chemical industry, and our robust manufacturing capabilities enable us to meet the demands of both small-scale research and large-scale industrial projects.

We invite inquiries for Triphenylsilane. NINGBO INNO PHARMCHEM CO.,LTD. offers competitive prices and flexible packaging options to suit diverse customer requirements. For businesses and researchers looking to buy or purchase this essential chemical with confidence in its purity and performance, we are your trusted partner. Our dedicated team is ready to provide comprehensive support and ensure a seamless procurement experience. Choose NINGBO INNO PHARMCHEM CO.,LTD. for your Triphenylsilane needs and experience the difference that quality and reliability make.