For professionals in the chemical and materials science industries, a deep understanding of key intermediates is essential for driving innovation. 1-Benzofuran-5-ol, identified by its CAS number 13196-10-6, is a versatile fine chemical intermediate that plays a significant role in various advanced applications, particularly in the fields of optoelectronics and conductive polymers.

Chemically, 1-Benzofuran-5-ol, also known by synonyms such as 5-Hydroxybenzofuran and Benzofuran-5-ol, is characterized by its molecular formula C8H6O2 and a molecular weight of approximately 134.13 g/mol. Its structure features a benzofuran core with a hydroxyl group at the 5-position, which imparts specific reactivity and properties. Physically, it is often described as a white solid. Key chemical properties include its melting point, typically around 186-187°C, and a boiling point of approximately 247.1°C at standard pressure. Its density is around 1.280 g/cm³.

The synthesis of 1-Benzofuran-5-ol is a process that requires precision and controlled chemical reactions. A common method involves starting with precursors like 5-methoxybenzofuran. For instance, a typical synthesis might involve dissolving 5-methoxybenzofuran in a solvent such as dichloromethane (DCM) under cooled conditions. Boron tribromide (BBr3) is then added as a demethylating agent. The reaction mixture is stirred at low temperatures and then allowed to warm to room temperature to complete the deprotection. Following the reaction, the mixture is quenched, neutralized, and extracted. The organic phases are dried and concentrated to yield the crude product, which, depending on the reaction conditions and desired purity, can be used directly or further purified. This process, when optimized by experienced manufacturers, yields 1-Benzofuran-5-ol with high purity, often exceeding 97%.

The utility of 1-Benzofuran-5-ol stems from its reactivity and structural features, making it a valuable building block. Its primary applications include the preparation of conductive polymer complexes, where it contributes to charge transport properties, and the synthesis of optoelectronic materials for devices like OLEDs and solar cells. It is also utilized in the synthesis of various biological inhibitors, pointing to its potential in pharmaceutical research and development. For those looking to purchase 1-Benzofuran-5-ol, understanding these properties and synthesis routes can help in selecting appropriate suppliers and ensuring product quality.

In essence, 1-Benzofuran-5-ol (CAS 13196-10-6) is a multifaceted fine chemical intermediate. Its well-defined properties and established synthesis methods make it a reliable component for advanced material development. We are a dedicated manufacturer and supplier offering high-purity 1-Benzofuran-5-ol. For detailed specifications, pricing inquiries, or bulk purchase requests, please do not hesitate to contact us.