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The landscape of chemical synthesis is continuously evolving, with a constant demand for sophisticated building blocks that enable the creation of novel and potent molecules. 2,4-Dichloro-5-iodopyrimidine, bearing the CAS number 13544-44-0, is a prime example of such a critical intermediate. Its unique chemical structure, featuring a pyrimidine core adorned with two chlorine atoms and an iodine atom, imparts a high degree of reactivity and selectivity, making it invaluable for organic chemists and pharmaceutical scientists.
Understanding the fundamental properties of 2,4-Dichloro-5-iodopyrimidine is key to leveraging its full synthetic potential. Typically appearing as an off-white crystalline powder, this compound boasts a purity level of 97% or higher, a standard that ensures its suitability for demanding applications. Its molecular formula, C4HCl2IN2, and molecular weight of approximately 274.87 g/mol are crucial data points for stoichiometric calculations in complex reaction schemes. The presence of reactive halogen sites allows for a variety of substitution and coupling reactions, which are foundational in building larger, more complex organic structures.
The primary applications of 2,4-Dichloro-5-iodopyrimidine are deeply rooted in the pharmaceutical industry. It serves as a vital intermediate in the synthesis of dipeptidyl peptidase IV (DPP-IV) inhibitors, a class of drugs widely prescribed for the management of type 2 diabetes. By enhancing the levels of incretin hormones, DPP-IV inhibitors help to regulate blood glucose levels. Furthermore, this versatile pyrimidine derivative is employed in the development of VLA-4 antagonists. These molecules are being investigated for their therapeutic benefits in treating a range of inflammatory and autoimmune diseases, highlighting the compound's importance in cutting-edge medicinal chemistry.
For researchers and procurement managers seeking to buy 2,4-Dichloro-5-iodopyrimidine, identifying reliable suppliers is essential. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., based in China, offer this high-purity intermediate, ensuring that research projects and production scales can proceed without interruption. Engaging with such suppliers provides access to essential technical data, competitive pricing, and a commitment to quality that is critical in the pharmaceutical supply chain.
The strategic use of 2,4-Dichloro-5-iodopyrimidine in developing novel therapeutics underscores its importance in modern synthetic chemistry. By understanding its properties and applications, and by partnering with reputable chemical manufacturers, scientists can efficiently advance their research goals and contribute to the development of life-changing medicines. NINGBO INNO PHARMCHEM CO.,LTD. stands ready to support these endeavors by providing consistent quality and supply of this crucial chemical intermediate.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
