For scientists and procurement specialists engaged in organic chemistry and pharmaceutical development, a thorough understanding of chemical intermediates is vital. 2-Bromo-5-fluorobenzyl Bromide (CAS 112399-50-5) is one such compound whose properties and correct handling are key to successful synthesis. This article explores its characteristics and provides insights for those looking to purchase this reagent from reliable sources.

Key Chemical and Physical Properties

2-Bromo-5-fluorobenzyl Bromide typically presents as a white powder, indicating its solid state at room temperature. Its melting point generally falls within the range of 33-36°C, and it has a boiling point of approximately 89-90°C at 1 mmHg. With a density of around 1.92 g/mL, it is a relatively dense compound. The compound's assay purity is usually specified at 97% or higher (e.g., ≥98.0%), which is critical for its efficacy in precise chemical reactions. Its appearance as a white to almost white solid underscores its quality and suitability for sensitive synthetic processes.

Safety and Handling Considerations

This chemical is known to be corrosive and a lachrymator, meaning it can cause severe skin burns, eye damage, and respiratory irritation. Therefore, appropriate personal protective equipment (PPE) is essential when handling it. This includes chemical-resistant gloves, safety goggles or a face shield, and lab coats. Work should ideally be conducted in a well-ventilated area, such as a fume hood, to minimize exposure to vapors. Special attention should be paid to storage conditions: it is recommended to store 2-Bromo-5-fluorobenzyl Bromide in a cool, dry place, typically between 2-8°C, away from incompatible materials like strong oxidizing agents. Protecting it from electrostatic charges is also advised.

Sourcing and Procurement from Leading Suppliers

When you need to buy 2-bromo-5-fluorobenzyl bromide, partnering with a reputable manufacturer or supplier is crucial for ensuring product quality and safety. Chinese chemical companies are prominent providers of this intermediate, offering competitive prices. When inquiring about 2-bromo-5-fluorobenzyl bromide price, it is important to confirm the purity, packaging (e.g., 5g, 10g, 100g, or bulk packages), and the supplier's adherence to safety and handling standards. As a trusted CAS 112399-50-5 supplier, we are committed to providing detailed product information and reliable sourcing solutions.

Applications in Synthesis

The primary application of 2-Bromo-5-fluorobenzyl Bromide is as a key intermediate in organic synthesis, particularly for the pharmaceutical industry. Its ability to undergo alkylation reactions makes it valuable for constructing complex molecular structures, such as Benzazepines. Researchers and industrial chemists rely on this compound for its predictable reactivity and the high purity that facilitates successful synthetic outcomes. For those seeking to purchase this reagent, understanding its properties is the first step towards effective and safe utilization.