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Understanding 2-Chloropyrazine (CAS 14508-49-7): Properties, Applications, and Procurement

2-Chloropyrazine (CAS 14508-49-7) is a heterocyclic organic compound that has garnered significant attention in various industrial sectors due to its unique chemical properties and versatile applications. Understanding its characteristics is crucial for researchers, formulators, and procurement specialists looking to leverage its potential.

Chemically, 2-Chloropyrazine is characterized by a pyrazine ring substituted with a chlorine atom. This chlorine atom imparts high reactivity, making it an excellent intermediate for nucleophilic substitution reactions. This property allows for the introduction of diverse functional groups, leading to the synthesis of a wide array of derivative compounds. Physically, it typically appears as a clear, colorless to light yellow liquid, with a molecular weight of approximately 114.53 g/mol. Its boiling point is around 153-154 °C, and it is generally soluble in common organic solvents like methanol and ethanol, though less so in water.

The applications of 2-Chloropyrazine are broad and impactful. In the pharmaceutical industry, it serves as a vital intermediate for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of antibacterial agents and drugs targeting the central nervous system. Its structural features contribute to the biological activity of these medications. In the agrochemical sector, it is used to create low-toxicity, high-efficiency pesticides, offering targeted protection for crops against pests and diseases. Beyond these primary uses, it also finds application as a building block in the synthesis of fine chemicals such as dyes, food additives, and fragrances, as well as in material science for developing functional materials like conductive polymers.

For organizations looking to procure 2-Chloropyrazine, sourcing from reliable manufacturers is key. Suppliers from China, for example, often provide high-purity grades (e.g., 99%) at competitive wholesale prices. When making a purchase, it is advisable to confirm specifications, inquire about minimum order quantities, and ensure the supplier can offer a stable and consistent supply chain. Understanding the product's CAS number (14508-49-7) and its chemical formula (C4H3ClN2) is essential for accurate sourcing. Whether for research and development or large-scale industrial production, 2-Chloropyrazine remains an indispensable intermediate in modern chemical synthesis.

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