For professionals in the chemical and pharmaceutical industries, a thorough understanding of key intermediates is essential for innovation and efficient production. 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline, identified by its CAS number 74852-62-3, is a compound of significant interest due to its role as a precursor in the synthesis of vital pharmaceutical products. This article aims to provide a comprehensive overview of its properties and guide potential buyers on how to source it effectively from reliable manufacturers in China.
Chemical Properties and Specifications
4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline is an organic compound with the molecular formula C17H21N3O and a molecular weight of 283.37 g/mol. Its physical characteristics typically include a Dark Purple to Dark Grey Solid appearance. A key indicator of its quality is its purity, which from reputable suppliers often exceeds 95%, verified by analytical methods such as HPLC. The compound has a reported melting point of around 186°C, and it is generally stable under normal ambient conditions, making it suitable for standard laboratory and industrial handling procedures. For procurement, it's important to check the specific storage recommendations provided by the manufacturer, which may include storage under inert atmosphere.
Applications as a Pharmaceutical Intermediate
The primary utility of 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline lies in its function as a crucial intermediate in the synthesis of Itraconazole. Itraconazole is a widely prescribed antifungal medication belonging to the triazole class, effective against a broad spectrum of fungal pathogens. The structural features of 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline are integral to building the complex molecular framework of Itraconazole, ensuring its therapeutic efficacy. Pharmaceutical companies that produce Itraconazole rely heavily on a consistent and high-quality supply of this intermediate to meet global demand.
Strategic Sourcing of the Intermediate
When seeking to buy 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline, it is advisable to engage with established chemical companies that specialize in pharmaceutical intermediates. Manufacturers in China are a primary source for this compound, offering competitive prices and reliable supply chains. Key steps for effective sourcing include:
By understanding the chemical properties and applications of 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline, and by partnering with trustworthy chemical suppliers, pharmaceutical professionals can ensure the efficient and successful development and manufacturing of essential antifungal treatments.
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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