For any chemist engaged in intricate organic synthesis, a thorough understanding of the building blocks they use is fundamental. 4-Aminophthalic Anhydride, identified by CAS number 17395-99-2, is a chemical intermediate that offers a unique combination of reactivity and structural utility. Its chemical structure features both an anhydride group and an aromatic amine, making it a versatile precursor for a wide array of organic transformations. This article aims to provide chemists and product formulators with a clear overview of its properties and the advantages it offers when you buy it from a trusted manufacturer.

Chemical Structure and Reactivity Insights

The molecular formula of 4-Aminophthalic Anhydride is C8H5NO3. The core of its structure is a benzene ring fused with a five-membered anhydride ring, with an amine group attached to the benzene ring at the '4' position relative to the anhydride. This specific arrangement dictates its chemical behavior:

• Anhydride Reactivity: The anhydride moiety is susceptible to nucleophilic attack, readily reacting with alcohols to form esters, with amines to form amides or imides, and with water to revert to the corresponding dicarboxylic acid. This makes it an excellent acylating agent.
• Amine Reactivity: The primary amine group (-NH2) is nucleophilic and can participate in reactions such as acylation, alkylation, diazotization, and condensation, allowing for further functionalization of the molecule.

These dual reactive sites make 4-Aminophthalic Anhydride a highly valuable component in multi-step syntheses, enabling the construction of complex molecular scaffolds used in pharmaceuticals, dyes, and specialty chemicals.

Key Physical Properties and Specifications

When considering the purchase of 4-Aminophthalic Anhydride, chemists will find its physical properties informative:

• Appearance: It is typically supplied as a white powder, which is a standard form for many solid organic intermediates.
• Purity: For its intended applications, particularly in API synthesis, a high purity level of ≥99% is generally required. This ensures predictable reaction outcomes and minimizes the generation of unwanted byproducts.
• Synonyms: Familiarity with synonyms such as 3-Aminophthalic anhydride is useful for literature searches and cross-referencing.

As a supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides this intermediate with guaranteed purity, supporting your research and development needs. Understanding these properties is essential before you buy to ensure compatibility with your specific synthetic routes.

Importance in the Supply Chain for Researchers

Researchers and procurement specialists looking to buy 4-Aminophthalic Anhydride should prioritize sourcing from reliable manufacturers and suppliers. The consistent quality and availability of this chemical intermediate from providers like NINGBO INNO PHARMCHEM CO.,LTD. are critical for the seamless progression of research projects and the scaling up of production processes. By ensuring a steady supply of high-quality 4-Aminophthalic Anhydride, chemists can confidently pursue novel synthetic targets and develop innovative products.