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Understanding 4-Bromothiophenol (CAS 106-53-6): Properties, Uses, and Sourcing

4-Bromothiophenol, identified by its CAS registry number 106-53-6, is a chemical compound of significant importance across several industrial sectors, most notably in pharmaceuticals and diagnostic reagent development. Understanding its properties and applications is key for any B2B professional involved in chemical procurement or research and development. This article aims to provide a comprehensive overview, from chemical characteristics to sourcing strategies, with a focus on reliable supply from China manufacturers.

The chemical profile of 4-bromothiophenol is well-defined. Its molecular formula is C6H5BrS, with a molecular weight of approximately 189.07 g/mol. As per available data, it typically presents as a white to beige crystalline powder. Its physical properties, such as a melting point range of 73-76 °C and a boiling point of 239 °C, are critical parameters for its handling, storage, and use in synthesis. These specifications highlight its nature as a stable solid at room temperature, often requiring refrigerated storage for optimal preservation, as indicated by some suppliers.

The primary utility of 4-bromothiophenol lies in its role as a chemical intermediate. In the pharmaceutical industry, it serves as a vital building block for synthesizing active pharmaceutical ingredients (APIs) and complex drug molecules. Its reactive bromine atom and thiol group allow for diverse chemical transformations, including coupling reactions essential for constructing elaborate molecular structures. For diagnostic reagent manufacturers, it is instrumental in creating labeling agents, probes, and conjugated biomolecules that form the basis of numerous diagnostic tests.

For businesses looking to buy 4-bromothiophenol, sourcing from China offers a compelling proposition. Chinese manufacturers are prominent global suppliers of a wide range of fine chemicals and pharmaceutical intermediates. They often provide 4-bromothiophenol at competitive price points due to economies of scale and efficient production processes. Procurement managers should prioritize working with suppliers who demonstrate a commitment to quality assurance, providing detailed CoAs and ensuring batch-to-batch consistency. When requesting a quote, specify the required purity and quantity to receive accurate pricing information.

Furthermore, the availability of technical documentation, such as Safety Data Sheets (SDS), is crucial for understanding the safe handling and regulatory compliance associated with 4-bromothiophenol. Reliable suppliers will readily provide these documents. For researchers and product developers, this ensures that they can integrate the compound into their workflows safely and effectively.

In conclusion, 4-Bromothiophenol (CAS 106-53-6) is a high-value chemical intermediate with diverse and critical applications. By understanding its properties and prioritizing reputable manufacturers and suppliers, particularly in China, businesses can secure a high-quality and cost-effective supply, thereby supporting their advancements in pharmaceutical development and diagnostic technologies.

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