For professionals in the chemical, pharmaceutical, and flavor & fragrance industries, a thorough understanding of key chemical compounds is essential. 4'-Methoxyacetophenone, identified by CAS number 100-06-1, is a versatile aromatic ketone that plays a significant role in numerous industrial processes. This article provides an in-depth look at its properties, synthesis, and diverse applications, highlighting why it's a sought-after raw material for manufacturers and researchers alike.

Physical and Chemical Properties:
4'-Methoxyacetophenone typically presents as white to pale yellow crystals. It is characterized by a distinct sweet aroma, often described as hawthorn-like, with nuances of anisic, powdery, and balsamic notes. Its molecular formula is C9H10O2, and it has a molecular weight of approximately 150.18 g/mol. It exhibits moderate solubility in water and is soluble in common organic solvents like alcohol and fixed oils. Key physical properties include a melting point around 36-40 °C and a boiling point of approximately 256.4 °C at atmospheric pressure. The compound's structure, featuring a methoxy group and a ketone functional group on a phenyl ring, dictates its reactivity and suitability for various chemical transformations.

Synthesis Methods:
The primary industrial method for synthesizing 4'-Methoxyacetophenone involves the Friedel-Crafts acetylation of anisole. This reaction is typically catalyzed by Lewis acids such as aluminum chloride or boron trifluoride, often in the presence of acetyl chloride or acetic anhydride. Modern advancements have explored the use of solid catalysts like zeolites in continuous flow processes to enhance efficiency and sustainability. For businesses looking to buy this compound, understanding the synthesis process can provide insight into potential impurity profiles and quality control measures.

Diverse Industrial Applications:
The utility of 4'-Methoxyacetophenone spans multiple sectors:

• Flavor and Fragrance Industry: Its pleasant aroma and taste make it an indispensable ingredient for creating sweet, floral, and fruity notes in perfumes, cosmetics, food products, and beverages. It is widely used to impart hawthorn, anisic, and vanilla-like characteristics.
• Pharmaceutical Intermediate: The compound serves as a crucial building block in the synthesis of various pharmaceutical drugs and active pharmaceutical ingredients (APIs). Its reactive sites allow for the construction of complex molecular structures essential for medicinal chemistry.
• Polymer and Resin Production: 4'-Methoxyacetophenone can be used as a precursor or co-monomer in the synthesis of specialized polymers and resins, contributing to materials with desirable properties such as enhanced durability and thermal resistance.
• Research and Development: In academic and industrial laboratories, it is employed as a reagent in organic synthesis for developing novel compounds and exploring new chemical reactions.

For manufacturers and researchers seeking a reliable source for high-purity 4'-Methoxyacetophenone, NINGBO INNO PHARMCHEM CO.,LTD. offers a consistent supply. We provide this essential chemical for sale, backed by stringent quality control and a commitment to customer satisfaction. Contact us today to request a quote and explore how our product can support your applications.