For professionals working in chemical synthesis and manufacturing, a thorough understanding of the properties and handling requirements of key intermediates is vital. 4-Methylpyridine-2-carboxaldehyde (CAS: 53547-60-7) is one such compound, frequently utilized in pharmaceutical and fine chemical industries. This article provides a comprehensive overview of its characteristics and best practices for handling.

Key Physical and Chemical Properties

4-Methylpyridine-2-carboxaldehyde is an organic compound with the molecular formula C7H7NO and a molecular weight of 121.14 g/mol. It typically appears as a clear to light yellow liquid. Its key properties include:

• Boiling Point: Approximately 208.8°C at 760 mmHg, though lower boiling points are reported under reduced pressure (e.g., 82-85°C at 11 mmHg).
• Flash Point: Around 84.3°C, indicating it is a combustible liquid.
• Density: Approximately 1.095 g/cm³ at 25°C.
• Refractive Index: Typically around 1.563.
• Purity: Commonly supplied with a minimum purity of 95%.
• Solubility: Generally soluble in organic solvents.

Safe Handling and Storage Guidelines

Given its properties, proper handling and storage of 4-Methylpyridine-2-carboxaldehyde are crucial for safety and product integrity:

• Storage Conditions: It is recommended to store this compound in a cool, dry, and well-ventilated area, away from incompatible substances. Some suppliers recommend storage under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2-8°C, especially for long-term preservation.
• Incompatible Materials: Avoid contact with strong oxidizing agents, strong acids, and strong bases, which could lead to hazardous reactions.
• Personal Protective Equipment (PPE): When handling, always wear appropriate PPE, including safety goggles, chemical-resistant gloves (such as nitrile or neoprene), and protective clothing. Work in a well-ventilated area or under a fume hood to avoid inhalation of vapors.
• Fire Safety: As a combustible liquid, keep away from open flames, sparks, and heat sources. Use appropriate fire extinguishing media such as dry chemical, CO2, or foam.

Procurement Considerations

When you are looking to buy 4-Methylpyridine-2-carboxaldehyde, whether from a manufacturer or a distributor, always refer to the Safety Data Sheet (SDS) provided by the supplier. The SDS contains detailed information on hazards, safe handling, first aid measures, and disposal. Reliable suppliers will provide this document readily. If you are searching for 'CAS 53547-60-7 handling' or '4-methylpyridine-2-carboxaldehyde safety,' consulting the SDS and product specifications from your chosen supplier is the most effective way to ensure safe and compliant usage.