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Understanding 5-Mercapto-1-methyltetrazole: Properties and Sourcing

In the realm of chemical synthesis, understanding the properties of key intermediates is essential for successful application and procurement. 5-Mercapto-1-methyltetrazole, identified by CAS number 13183-79-4, is a versatile organic compound that finds significant use in the pharmaceutical industry. This article delves into its fundamental properties and provides practical guidance for sourcing this important chemical.

5-Mercapto-1-methyltetrazole is a heterocyclic organic compound with the molecular formula C2H4N4S and a molecular weight of approximately 116.14 g/mol. It is typically characterized by its appearance as a white crystalline powder. Key physical properties include a melting point range of 125-128 °C and a density of around 1.69 g/cm³. While its boiling point is predicted, its solid form at room temperature and stable nature under normal conditions make it a convenient intermediate to handle and store. For optimal preservation, it is recommended to store 5-Mercapto-1-methyltetrazole in a cool, dry place, in a tightly sealed container, away from incompatible materials.

The primary application driving the demand for 5-Mercapto-1-methyltetrazole is its role as a crucial pharmaceutical intermediate. It serves as a vital component in the synthesis of numerous cephalosporin antibiotics, a class of drugs critical for treating bacterial infections. Its chemical structure lends itself to forming specific side chains required for the efficacy of antibiotics such as cefotaxazole, cefmetazole sodium, and cefalotidazole. Therefore, ensuring a high purity level, typically 95% or higher, is paramount when sourcing this compound for pharmaceutical use.

For researchers and procurement managers looking to buy 5-mercapto-1-methyltetrazole, identifying reliable manufacturers and suppliers is key. Companies in China are prominent sources for this intermediate, offering competitive pricing and substantial production capabilities. When searching for a pharmaceutical intermediate supplier, it's advisable to look for those who can provide detailed technical specifications, batch-specific Certificates of Analysis (CoAs), and potentially free samples for quality verification. Engaging with a CAS 13183-79-4 manufacturer that prioritizes quality control and offers good customer support can streamline the procurement process.

In essence, 5-Mercapto-1-methyltetrazole is a compound of significant importance in pharmaceutical synthesis. Understanding its properties, applications, and the best practices for sourcing from reputable global manufacturers will enable businesses to secure a consistent supply of this critical intermediate, thereby contributing to the production of essential medicines.

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