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Understanding Amino Acid Derivatives: A Deep Dive into Boc-Cys(Acm)-OH

The field of chemistry relies heavily on the availability and precise understanding of various chemical compounds, particularly amino acid derivatives, which are the fundamental building blocks of peptides and proteins. Among these, Boc-Cys(Acm)-OH, scientifically identified as N-Boc-S-acetamidomethyl-L-cysteine with CAS number 19746-37-3, holds significant importance. As a specialist supplier of amino acid derivatives, we aim to provide in-depth knowledge about this compound and its utility in scientific research and development.

Boc-Cys(Acm)-OH is a derivative of the amino acid cysteine, distinguished by two key protecting groups. The tert-butyloxycarbonyl (Boc) group is attached to the alpha-amino group, a common protection strategy in peptide synthesis that is easily removed under acidic conditions. The acetamidomethyl (Acm) group is attached to the thiol side chain of cysteine. This S-protection is crucial because the thiol group of cysteine is highly reactive and can readily form disulfide bonds. The Acm group renders the thiol inert during standard peptide synthesis steps, such as coupling and Boc deprotection, while allowing for selective cleavage and subsequent oxidation to form disulfide bridges when desired. This controlled introduction of disulfide bonds is vital for creating the specific three-dimensional structures of many biologically active peptides, including therapeutic agents.

The physical properties of Boc-Cys(Acm)-OH typically include its appearance as a white powder, a melting point in the range of 103-117°C, and a molecular weight of approximately 292.35 g/mol. For researchers looking to buy Boc-Cys(Acm)-OH, understanding these properties, along with the purity specifications (often >98% or >99% by HPLC), is essential for successful experimental outcomes. As a manufacturer and supplier in China, we ensure that our product meets these critical standards, providing researchers with a reliable source for their synthetic needs.

The applications of Boc-Cys(Acm)-OH are primarily centered around peptide synthesis, especially for peptides that require disulfide cross-linking for their structural integrity and biological function. This includes research into peptide hormones, enzyme inhibitors, and other biologically active peptides. Furthermore, it finds utility in protein modification studies and the development of peptidomimetics. When scientists search for CAS 19746-37-3, they are seeking a dependable supply of this specialized reagent. We are committed to meeting this demand by offering high-quality N-Boc-S-acetamidomethyl-L-cysteine at competitive prices, supported by comprehensive technical documentation.

In summary, Boc-Cys(Acm)-OH is a sophisticated amino acid derivative indispensable for modern peptide chemistry. Its carefully designed protecting groups enable precise control over disulfide bond formation, a key feature for many peptide therapeutics and research molecules. We invite you to explore our range of high-quality amino acid derivatives. Contact us today to learn more about Boc-Cys(Acm)-OH, discuss your project requirements, and secure a reliable supply from a trusted manufacturer.

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