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Understanding BIS(O-TRIMETHYLSILYL)THYMINE: Properties and Applications

In the realm of organic chemistry, intermediates that facilitate complex transformations are highly prized. BIS(O-TRIMETHYLSILYL)THYMINE, with CAS number 7288-28-0, is one such compound that offers significant advantages to chemists. This article aims to provide a comprehensive overview of its properties and highlight its essential applications, particularly as a reactive intermediate in synthesis.

BIS(O-TRIMETHYLSILYL)THYMINE is characterized by its white or light yellow crystalline powder appearance. It has a melting point range of 73-75 °C, indicating its solid state at room temperature. A key characteristic of this compound is its sensitivity to moisture, which necessitates careful handling and storage to maintain its reactivity and purity. Chemically, it is known as a reactive intermediate for the preparation of nucleosides, making it a fundamental building block in various synthetic pathways. Its molecular formula is C11H22N2O2Si2, and it has a molecular weight of 270.48.

The primary application of BIS(O-TRIMETHYLSILYL)THYMINE lies in organic synthesis, specifically in the preparation of nucleosides. This process is crucial for creating a wide array of biologically active molecules, including those used in antiviral and anticancer therapies. The trimethylsilyl groups protect the oxygen atoms of thymine, allowing for controlled reactions, such as glycosylation, which are essential for forming the nucleoside backbone. This makes it an indispensable component for researchers and manufacturers in the pharmaceutical and fine chemical industries.

Sourcing high-quality BIS(O-TRIMETHYLSILYL)THYMINE is vital for achieving reliable results. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted manufacturer and supplier in China, providing this compound with a purity of 98%. For those looking to buy BIS(O-TRIMETHYLSILYL)THYMINE, choosing a supplier that emphasizes quality and consistency is paramount to the success of your synthetic projects. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting your chemical needs with dependable products.

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