In the realm of peptide chemistry, precision and efficiency are key. Boc-Asp(OtBu)-OSu (CAS: 50715-50-9) is a specialized amino acid derivative that plays a crucial role in facilitating the synthesis of complex peptides. As a prominent chemical manufacturer, we aim to provide a deep understanding of this compound, its properties, and its essential applications, guiding our clients on how to best purchase it for their research and development needs.

Boc-Asp(OtBu)-OSu, also recognized by its synonyms such as N-alpha-tert-butoxycarbonyl-L-aspartic acid beta-tert-butyl ester alpha-N-hydroxysuccinimide ester, is a versatile building block. Its molecular structure is meticulously designed to support the demanding requirements of modern peptide synthesis. The presence of the tert-butoxycarbonyl (Boc) group on the alpha-amino functionality ensures it remains unreactive during coupling steps, while the beta-tert-butyl ester protects the side-chain carboxyl group, offering orthogonal protection. The alpha-carboxyl group is activated as an N-hydroxysuccinimide (OSu) ester, rendering it highly susceptible to nucleophilic attack by the amino group of another amino acid or peptide fragment. This feature is central to its function, making it a highly sought-after reagent for those looking to buy efficiently coupling amino acid derivatives.

The applications of Boc-Asp(OtBu)-OSu are primarily centered around peptide synthesis. It is indispensable for introducing aspartic acid residues into peptide sequences, particularly in solid-phase peptide synthesis (SPPS) where repetitive coupling and deprotection steps are performed. Its excellent reactivity and the stability of its protecting groups contribute to higher yields and purer peptide products, which is critical for pharmaceutical research and drug discovery. For example, in the synthesis of peptide hormones, enzymes, or therapeutic peptides, the accurate and efficient incorporation of modified amino acids like aspartic acid is essential. Researchers often inquire about the Boc-Asp(OtBu)-OSu price from established suppliers to ensure cost-effectiveness in their synthesis campaigns.

When seeking to purchase Boc-Asp(OtBu)-OSu, it is important to partner with reputable manufacturers and suppliers who guarantee product quality and consistency. Factors such as purity (often specified by HPLC), physical form (typically a white powder), and storage conditions (often requiring refrigeration) are crucial considerations. Understanding the chemical properties, such as its melting point and solubility in typical organic solvents, also aids in its effective use. For those in need of bulk quantities or specific packaging, contacting a manufacturer directly for a quote can provide the best procurement strategy. We are dedicated to serving the scientific community by offering high-grade Boc-Asp(OtBu)-OSu, making it easier for you to buy the materials you need for your groundbreaking research.