Chemical compounds are often identified by their CAS Registry Numbers, a unique numerical identifier that ensures unambiguous reference. For 2-(3-Amino-4-chloro-benzoyl)benzoic acid, this number is CAS 118-04-7. This designation is critical for researchers, manufacturers, and regulators to accurately identify and discuss the compound. This article aims to provide a comprehensive understanding of CAS 118-04-7, covering its physical and chemical properties, its primary applications, and its importance within the broader chemical landscape.

Physically, 2-(3-Amino-4-chloro-benzoyl)benzoic acid is typically described as a yellow solid. Its melting point, a key indicator of purity and identity, generally falls within the range of 171-173°C, although slight variations can occur depending on the manufacturing process and purity. The compound exhibits limited solubility in water but is more soluble in organic solvents such as methanol and DMSO. These solubility characteristics are important considerations for its use in various reaction media and formulation processes. The molecular formula, C14H10ClNO3, and a molecular weight of approximately 275.69 g/mol, provide further precise identification.

The primary significance of CAS 118-04-7 lies in its role as a pharmaceutical intermediate. It is a crucial precursor in the synthesis of chlorthalidone, a widely used diuretic medication. This application alone underscores the compound's importance in the healthcare sector. The intricate chemical structure of 2-(3-Amino-4-chloro-benzoyl)benzoic acid, featuring an amine group, a chlorine atom, and a benzoylbenzoic acid moiety, makes it a versatile building block. This structure allows for the targeted modifications necessary to synthesize complex drug molecules with specific therapeutic effects.

The demand for CAS 118-04-7 is closely tied to the market for chlorthalidone and other potential downstream products. Factors such as the prevalence of cardiovascular diseases and the need for effective treatments drive the demand for this intermediate. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. play a pivotal role in meeting this demand by ensuring a steady supply of high-quality material. Their expertise in chemical synthesis intermediate production ensures that researchers and drug manufacturers have access to a reliable source of CAS 118-04-7 for their critical work.

In conclusion, understanding the details associated with CAS 118-04-7 is essential for anyone involved in the chemical and pharmaceutical industries. Its physical properties, chemical structure, and critical applications as a pharmaceutical intermediate, particularly for chlorthalidone synthesis, highlight its considerable value. NINGBO INNO PHARMCHEM CO.,LTD.’s commitment to producing this compound to high standards ensures its continued availability for vital medical and research purposes.