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Understanding CAS 195447-63-3: A Key Fluorinated Pharmaceutical Intermediate

In the intricate world of pharmaceutical development, precise chemical intermediates are the bedrock upon which novel therapeutics are built. One such critical compound is 1-(2,2,2-trifluoroethyl)piperazine hydrochloride, identified by its CAS number 195447-63-3. This molecule serves as a vital building block, particularly valued for its incorporation of a trifluoroethyl group attached to a piperazine ring, a combination that offers unique advantages in medicinal chemistry.

The presence of fluorine atoms in organic molecules is a well-established strategy to modulate a drug's properties. Fluorination can enhance metabolic stability, improve lipophilicity, and influence binding interactions with biological targets, thereby potentially increasing efficacy and reducing side effects. The piperazine moiety, on the other hand, is a common scaffold in many drug classes, providing opportunities for targeted interactions and influencing solubility and bioavailability.

Consequently, 1-(2,2,2-trifluoroethyl)piperazine hydrochloride is a sought-after intermediate for researchers and manufacturers involved in synthesizing Active Pharmaceutical Ingredients (APIs) and drug candidates across various therapeutic areas, including antivirals, CNS agents, and oncology drugs. Its utility lies in its ability to be readily incorporated into larger, more complex molecular structures through standard organic synthesis techniques.

For professionals in the pharmaceutical industry, understanding how to effectively source and purchase CAS 195447-63-3 is crucial. This involves identifying reliable manufacturers, preferably those with a strong track record in producing high-purity intermediates. Suppliers offering products with guaranteed purity levels, such as 95% or higher, and providing comprehensive documentation like Certificates of Analysis (CoA), are highly preferred. Furthermore, the ability to procure this chemical in various quantities, from grams for research to kilograms for pilot-scale manufacturing, from a single, dependable supplier, streamlines the procurement process.

When seeking to buy 1-(2,2,2-trifluoroethyl)piperazine hydrochloride, consider manufacturers with robust quality control systems and efficient logistics. Engaging with a reputable chemical supplier from China can offer competitive pricing and assured availability, ensuring your research and development projects proceed without interruption. Prioritizing purity and supply chain reliability are key to unlocking the full potential of this important pharmaceutical intermediate.

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