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Understanding CAS 444731-75-3: Your Guide to a Key Pazopanib Precursor

For professionals in the pharmaceutical manufacturing and R&D sectors, precision and reliability in chemical sourcing are non-negotiable. CAS 444731-75-3, scientifically known as N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine, is a prime example of a high-value pharmaceutical intermediate. Its primary application lies in the synthesis of Pazopanib, a critical targeted therapy used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. As a key precursor, its consistent availability and high purity are essential for the successful production of this important anti-cancer medication.

N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine (CAS 444731-75-3) is characterized by its molecular formula C14H14ClN5 and a molecular weight of 287.75 g/mol. It typically presents as an off-white to light yellow solid, with a melting point range of 167-173°C. Its solubility in common organic solvents like chloroform and ethyl acetate (though slight) is important for synthetic chemists. Understanding these basic chemical properties is the first step for any researcher or procurement specialist looking to buy CAS 444731-75-3 for their projects.

The global pharmaceutical supply chain relies heavily on specialized chemical intermediates. Identifying a dependable N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine supplier is crucial for maintaining production schedules and ensuring product quality. We connect you with leading manufacturers in China who specialize in producing this intermediate to exacting standards, ensuring a consistent supply for your pharmaceutical needs. Whether you require small quantities for early-stage research or large volumes for commercial manufacturing, our network is equipped to serve your demands.

When evaluating the price of N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine, it's important to consider the overall value proposition, which includes not just cost but also purity, reliability, and regulatory compliance. By leveraging our sourcing expertise, you gain access to competitively priced materials without compromising on the critical quality parameters required for pharmaceutical applications. Our goal is to simplify your procurement process, allowing you to focus on innovation and production.

The synthesis of Pazopanib is a testament to modern medicinal chemistry, and intermediates like CAS 444731-75-3 are the backbone of this process. We are committed to being a trusted partner for companies looking to source this essential pharmaceutical intermediate. For detailed specifications, pricing, and to discuss your bulk purchase requirements, please contact us. Partner with us to secure a reliable supply of N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine and accelerate your pharmaceutical development.

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