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Cbz-D-Valine, cataloged under CAS number 1685-33-2, is a significant fine chemical that plays a crucial role as an intermediate in various chemical and pharmaceutical applications. This compound is essentially D-Valine with its alpha-amino group protected by the benzyloxycarbonyl (Cbz) moiety. This protection is key to its utility, allowing for controlled reactions in complex synthesis pathways. NINGBO INNO PHARMCHEM CO.,LTD. provides this vital chemical to meet the stringent requirements of the scientific community.
Chemically, Cbz-D-Valine (C13H17NO4, Molecular Weight: 251.28) typically appears as a white to off-white crystalline powder. Its melting point range, often cited between 58-60°C, is a critical indicator of its purity. The solubility of Cbz-D-Valine is notable in organic solvents such as chloroform, dichloromethane, and ethyl acetate, which are commonly used in synthesis. This solubility profile makes it amenable to various reaction conditions and purification techniques. The Cbz group is known for its stability under mildly acidic or basic conditions and its susceptibility to hydrogenolysis, a common method for its removal to reveal the free amine functionality.
The primary application of Cbz-D-Valine lies in its role as a protected amino acid building block. It is extensively used in the synthesis of peptides, where it ensures that the D-valine residue is incorporated precisely into the peptide chain without unwanted side reactions. Beyond peptide synthesis, Cbz-D-Valine serves as a valuable pharmaceutical intermediate for the creation of small molecules and drug candidates. Its structure can be further modified or incorporated into larger molecular frameworks to develop compounds with targeted biological activities.
For researchers and chemical manufacturers, sourcing high-quality Cbz-D-Valine is essential for the success of their synthetic endeavors. NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering products that meet high purity standards, ensuring reliable performance in critical applications. The availability of this fine chemical directly impacts the efficiency and success rate of projects in medicinal chemistry, biochemistry, and materials science.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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