For chemists and researchers working with advanced organic synthesis and pharmaceutical intermediates, a thorough understanding of chemical properties is fundamental. Cbz-L-Glutamic Acid 1-Benzyl Ester (CAS: 3705-42-8) is a prime example of a compound whose specific characteristics dictate its utility, particularly in peptide synthesis and as a precursor for neuroactive compounds. Delving into these properties ensures optimal handling, storage, and application.

The molecular formula for Cbz-L-Glutamic Acid 1-Benzyl Ester is C20H21NO6, with a molecular weight of approximately 371.38 g/mol. Its appearance is consistently described as a white powder, making it visually identifiable and easy to handle in laboratory settings. The melting point typically falls within the range of 95.0-105.0℃, a key parameter for quality control and identification. For those looking to buy this compound, verifying these physical properties is the first step in ensuring authenticity and quality from any supplier.

Solubility is another critical aspect. Cbz-L-Glutamic Acid 1-Benzyl Ester is noted to be soluble in common organic solvents such as Dimethyl Sulfoxide (DMSO) and Methanol. This characteristic is vital for its use in various reaction media, including those employed in solid-phase peptide synthesis. Its slight solubility in water means that aqueous-based reactions or purifications require careful consideration of solvent systems.

Storage recommendations are typically to keep the compound sealed and dry at room temperature. This standard practice helps prevent degradation from moisture and air, preserving its chemical integrity. When sourcing from a manufacturer in China, understanding these storage requirements is part of ensuring that the product arrives and remains viable for its intended purpose.

The chemical structure, featuring the Cbz protecting group on the amine and a benzyl ester on the gamma-carboxyl group of L-glutamic acid, provides the necessary stability and reactivity for controlled synthesis. These protecting groups can be selectively cleaved using standard deprotection protocols, such as catalytic hydrogenation, allowing for precise manipulation during complex molecular assembly. Researchers seeking a dependable pharmaceutical intermediate with well-defined chemical behavior will find this compound to be an excellent choice. To secure this high-quality material at a favorable price, engaging with reputable chemical providers is recommended.