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For researchers and production chemists working on complex synthesis projects, having a deep understanding of the chemical intermediates they use is fundamental. D-Tryptophan Methyl Ester Hydrochloride (CAS 14907-27-8) is a specialized amino acid derivative that serves as a key building block in various organic syntheses, most notably in the production of Tadalafil. This article aims to provide R&D scientists and procurement professionals with essential information on this compound.
D-Tryptophan Methyl Ester Hydrochloride is typically supplied as an off-white crystalline powder. Its chemical formula C12H15ClN2O2 and molecular weight of 254.71 are critical identifiers. For effective use in synthesis, understanding its properties such as melting point (213-216°C) and solubility (e.g., soluble in water, DMSO, methanol) is important. These characteristics influence reaction conditions, solvent choices, and purification strategies. When planning to buy this intermediate, it’s imperative to source it from reputable manufacturers who can provide detailed specifications and ensure its chiral integrity, as it is derived from D-Tryptophan.
The primary application of D-Tryptophan Methyl Ester Hydrochloride is its role as an intermediate in the synthesis of Tadalafil, a widely prescribed medication. This necessitates high purity levels, often exceeding 98.0%. Therefore, buyers should always prioritize suppliers who can offer consistent quality and provide comprehensive Certificates of Analysis. Sourcing this compound often involves working with specialized fine chemical suppliers or manufacturers, many of whom are located in China, offering competitive pricing and reliable availability for purchase.
As an R&D scientist or procurement manager, selecting the right supplier for D-Tryptophan Methyl Ester Hydrochloride involves assessing their technical expertise, manufacturing capabilities, and customer service. Beyond just the price, consider their ability to provide ongoing support and ensure a stable supply chain. Building a partnership with a manufacturer that understands the nuances of pharmaceutical intermediates like D-Tryptophan Methyl Ester Hydrochloride is crucial for the success of your synthesis projects and for securing the best price for your bulk requirements.
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