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Understanding Diethyl Dipropylmalonate: Properties and Synthesis for Industry

For professionals in the chemical, cosmetic, and pharmaceutical industries, a deep understanding of the compounds they work with is fundamental. Diethyl Dipropylmalonate, identified by its CAS number 6065-63-0, is a malonate ester with specific chemical properties that make it a valuable intermediate. This article aims to provide an overview of its characteristics and industrial synthesis, as relevant to procurement and R&D personnel.

The molecular formula of Diethyl Dipropylmalonate is C13H24O4, giving it a molecular weight of approximately 244.33 g/mol. This structure features a central malonic acid diethyl ester core with two propyl groups attached to the alpha-carbon. This specific arrangement of functional groups dictates its reactivity and utility in various synthetic pathways. The compound is often described by its synonyms, such as Diethyl 2,2-dipropylmalonate or Dipropylpropanedioic acid diethyl ester.

Industrially, Diethyl Dipropylmalonate is typically synthesized through esterification reactions. A common method involves the reaction of dipropylmalonic acid or its derivatives with ethanol in the presence of an acid catalyst. Alternatively, it can be prepared by alkylating diethyl malonate with propyl halides. Manufacturers who produce this chemical in bulk focus on optimizing these synthesis routes to achieve high yields and, crucially, high purity. Purity levels of 98% are standard for its commercial grades, ensuring its suitability for demanding applications.

The physical properties of Diethyl Dipropylmalonate are also important for handling and processing. While some sources may describe it as a white powder, it is more commonly encountered as a clear, colorless to light yellowish liquid at room temperature. Its boiling point is approximately 262.9 °C at 760 mmHg, and its density is around 0.976 g/cm³. These characteristics are critical for process engineers and safety officers when designing reaction vessels, storage facilities, and transportation protocols.

The EINECS number for Diethyl Dipropylmalonate is 227-998-2, an important identifier in European chemical regulations. For international buyers, understanding these identifiers and ensuring compliance with regional chemical inventories and regulations is part of the sourcing process.

The primary industrial applications of Diethyl Dipropylmalonate stem from its role as a versatile building block. Its use in the synthesis of pharmaceutical compounds, particularly in the production of anticonvulsant drugs, highlights its significance. In the cosmetics industry, it may be used as an emollient or to modify product texture. When looking to purchase this chemical, terms like 'Diethyl Dipropylmalonate properties', 'CAS 6065-63-0 synthesis', or 'buy high purity malonate ester' are often used by professionals seeking specific technical information and reliable supply.

For businesses aiming to secure a consistent supply of Diethyl Dipropylmalonate, partnering with manufacturers who prioritize efficient synthesis, stringent quality control, and global distribution is key. This ensures that the compound meets the required specifications for both R&D and large-scale industrial production.

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