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Understanding Fmoc-D-Valine (CAS 84624-17-9): Properties and Usage

Fmoc-D-Valine, identified by its CAS number 84624-17-9, stands as a critical component in the field of organic chemistry and pharmaceutical development. As an Fmoc-protected form of D-Valine, this compound is indispensable for peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methodologies. Understanding its properties is key to leveraging its full potential in research and manufacturing.

The chemical structure of Fmoc-D-Valine (C20H21NO4) boasts a molecular weight of 339.39 g/mol. It typically presents as a white powder, with reported melting points in the range of 143-144°C. Its solubility in various organic solvents like chloroform, DMF, DMSO, and methanol, though slight in some, is sufficient for common synthetic procedures. The ‘Fmoc’ group offers a protected amine functionality that can be cleaved under mild basic conditions, making it orthogonal to acid-labile protecting groups, a critical advantage in multi-step synthesis.

The significance of Fmoc-D-Valine as a pharmaceutical intermediate cannot be overstated. Its specific stereochemistry and protected amino group allow for controlled coupling reactions, facilitating the construction of complex peptide chains that form the basis of many modern therapeutics. Researchers often investigate Fmoc-D-Valine applications to synthesize novel drug candidates or to create peptide-based biomaterials. The consistent quality and high purity, often exceeding 99%, are hallmarks of reliable suppliers.

NINGBO INNO PHARMCHEM CO.,LTD. is a prominent Fmoc-D-Valine supplier in China, offering this vital compound to the global market. Our expertise in Fmoc-D-Valine synthesis ensures that we provide products meeting the stringent demands of the pharmaceutical and biotechnology industries. Whether you are performing intricate Fmoc-D-Valine for peptide synthesis projects or require it as a reference standard, NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent supply and competitive Fmoc-D-Valine price. Understanding the detailed N-Fmoc-D-valine properties is key for successful integration into your research protocols.

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