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Understanding Fmoc-Dab(Boc)-OH: Properties, Synthesis, and Suppliers

In the realm of organic synthesis and medicinal chemistry, certain specialized building blocks are indispensable for unlocking new possibilities. Fmoc-Dab(Boc)-OH stands out as one such compound, playing a critical role in the synthesis of peptides and complex organic molecules. Understanding its properties, how it's synthesized, and where to procure it reliably is key for researchers and manufacturers. NINGBO INNO PHARMCHEM CO.,LTD. provides a manufacturer's perspective on this important chemical.

Fmoc-Dab(Boc)-OH, also known by its CAS number 125238-99-5, is a differentially protected derivative of 2,4-diaminobutyric acid. The molecule features a 9-fluorenylmethoxycarbonyl (Fmoc) group protecting the alpha-amino group and a tert-butoxycarbonyl (Boc) group protecting the gamma-amino group. This dual protection is crucial for its primary application in solid-phase peptide synthesis (SPPS), allowing for selective deprotection and stepwise chain elongation. The molecular formula is C24H28N2O6, with a molecular weight of approximately 440.49 g/mol.

The synthesis of Fmoc-Dab(Boc)-OH typically involves a stepwise protection strategy starting from 2,4-diaminobutyric acid. One common pathway involves first protecting the gamma-amino group with a Boc anhydride derivative and then protecting the alpha-amino group with an Fmoc protecting agent, or vice-versa, depending on the specific synthetic route employed by the manufacturer. Achieving high purity is paramount, as impurities can negatively impact downstream reactions, particularly in sensitive peptide synthesis protocols. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. invest significantly in optimized synthesis and purification methods to ensure product quality.

When researchers are looking to buy Fmoc-Dab(Boc)-OH, they are often seeking a balance between competitive price and guaranteed purity. Sourcing from a direct manufacturer in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can offer a significant advantage. This direct route often leads to more transparent pricing and a more robust supply chain. We are committed to providing high-quality Fmoc-Dab(Boc)-OH at competitive price points, understanding the budget constraints often faced in research and development.

Finding reliable suppliers for specialized chemicals like Fmoc-Dab(Boc)-OH is crucial for ensuring project continuity. Factors to consider when selecting a supplier include their manufacturing capabilities, quality control processes, documentation (such as Certificates of Analysis), and customer support. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a dependable supplier, offering comprehensive product information and supporting our clients with their procurement needs. We encourage inquiries for quotes and samples to demonstrate the quality of our Fmoc-Dab(Boc)-OH.

In summary, Fmoc-Dab(Boc)-OH is a sophisticated chemical intermediate vital for advanced synthesis. Its unique properties, coupled with reliable manufacturing and supply, are essential for progress in peptide science and related fields. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to being a premier manufacturer and supplier, providing researchers and industries with the high-purity Fmoc-Dab(Boc)-OH they need to achieve their scientific and commercial goals.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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