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When sourcing histidine for industrial or research purposes, buyers often encounter two primary forms: L-Histidine Base and L-Histidine Hydrochloride. While both are derived from the essential amino acid L-Histidine, understanding their distinct properties and applications is crucial for making an informed purchase decision. As a leading manufacturer and supplier from China, we provide both forms and can guide you to the best choice for your specific needs.
L-Histidine Base (CAS 71-00-1) is the zwitterionic form of the amino acid. It is a white crystalline powder with good solubility in water and is known for its excellent buffering capacity, particularly at physiological pH. This makes it highly valuable in pharmaceutical formulations, especially for stabilizing biologics and in cell culture media. Its purity and specific chemical properties are often preferred when precise pH control is critical.
L-Histidine Hydrochloride (CAS 5934-29-2 for the monohydrate) is the salt formed by reacting L-Histidine with hydrochloric acid. It typically exhibits higher water solubility compared to the base form and is often used when greater solubility is required for a particular application. It is also a common choice in pharmaceutical excipients and nutritional supplements. The hydrochloride form can sometimes offer advantages in terms of stability or ease of handling in certain manufacturing processes.
The choice between L-Histidine Base and L-Histidine Hydrochloride often depends on the specific formulation requirements, desired pH range, and manufacturing process. Both are manufactured under strict quality controls by our company to ensure high purity and consistency. As a reliable China supplier, we can provide technical support to help you determine which form best suits your application. Whether you need the precise buffering of the base or the enhanced solubility of the hydrochloride, we are equipped to meet your demands with competitive pricing and dependable supply.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
