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Understanding L-N-Butylsulfonyl-P-Hydroxyphenylalanine: Properties and Uses

L-N-Butylsulfonyl-P-Hydroxyphenylalanine, identified by its CAS number 149490-60-8, is a chemical compound of significant interest within the pharmaceutical industry. As an advanced intermediate, it plays a pivotal role in the synthesis of certain therapeutic agents, most notably Tirofiban, which is used as an antithrombotic medication. For research scientists and procurement professionals, a comprehensive understanding of its properties and applications is essential for effective sourcing and utilization.

Chemically, this compound is characterized by its molecular formula C13H19NO5S and a molecular weight of approximately 301.36 g/mol. It presents as a white or off-white crystalline solid powder, with a melting point often cited around 121-124°C. The structure incorporates a butylsulfonyl group attached to the nitrogen atom of a modified tyrosine residue, which is key to its function as a synthetic precursor.

The primary application of L-N-Butylsulfonyl-P-Hydroxyphenylalanine lies in its use as an intermediate in the synthesis of Tirofiban and its labeled analogues. Tirofiban is a critical component in treatments aimed at preventing blood clots, particularly in patients with unstable angina or those undergoing certain cardiac procedures. The consistent demand for high-purity CAS 149490-60-8 reflects its importance in the production of these life-saving drugs.

For companies looking to buy L-N-Butylsulfonyl-P-Hydroxyphenylalanine, sourcing from reliable manufacturers, especially from China, offers cost-effectiveness and accessibility. Suppliers typically guarantee purity levels of 97-98% and provide detailed technical specifications. When evaluating potential vendors, it is advisable to inquire about their production capacity, quality control measures, and their ability to supply consistently. Understanding these aspects ensures that procurement managers can secure this vital intermediate for their pharmaceutical manufacturing needs.

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