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For R&D scientists and product formulators, a deep understanding of a chemical's properties is the bedrock of successful product development. Letrozole, identified by its CAS number 112809-51-5, is a compound that requires careful consideration of its physical and chemical characteristics. Its typical appearance as a white to off-white crystalline powder, along with its molecular formula (C17H11N5) and molecular weight (285.30), provides initial insights into its handling and potential applications.
Delving deeper, the melting point of Letrozole, often cited in the range of 181-183°C, is a critical parameter for its stability and processing conditions. This solid state at room temperature influences how it is stored, transported, and incorporated into various formulations. Understanding its solubility profile is also crucial for formulators. While Letrozole exhibits good solubility in DMSO (>50 mg/mL), its solubility in water and ethanol is typically less than 1 mg/mL, and less than 1 mg/mL, respectively. This differential solubility guides its use in different solvent systems for applications like photoresist chemicals or other advanced materials.
The density of Letrozole (1.21g/cm3) and its boiling point (374.4 °C at 760 mmHg) further inform its behavior under various physical conditions. For product formulators, knowing these properties helps in predicting how the compound will behave during mixing, heating, or other processing steps. The flash point of 180.3 °C indicates a relatively low flammability risk, contributing to safer handling procedures in laboratory and manufacturing environments.
When considering the purchase of Letrozole, R&D scientists often seek high-purity grades, frequently specified as >99% (HPLC). This stringent purity level is vital for ensuring predictable reactions and desired outcomes, especially in sensitive applications. Manufacturers supplying Letrozole must provide comprehensive documentation, including Certificates of Analysis, to verify these critical properties. For those looking to buy Letrozole, understanding these detailed properties allows for informed selection of the best grade for their specific formulation needs.
In summary, the physical and chemical properties of Letrozole CAS 112809-51-5 are key determinants of its utility in product formulation. R&D scientists and product formulators should leverage this information when sourcing from suppliers, ensuring they receive a compound that meets their exact specifications for optimal performance in their target applications. Always inquire about these properties when requesting a quote from manufacturers and suppliers.
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