Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
Methotrexate (CAS 59-05-2), a cornerstone in both cancer chemotherapy and the management of autoimmune diseases, demands a thorough understanding of its complex interactions and necessary precautions. As a potent antifolate, its efficacy is matched by a need for careful administration to mitigate potential risks. Exploring the nuances of methotrexate uses, from treating aggressive cancers to alleviating symptoms of rheumatoid arthritis and psoriasis, reveals its broad therapeutic scope.
A critical aspect of Methotrexate therapy is its potential for significant drug interactions. Many common medications can affect its metabolism or excretion, thereby increasing the risk of toxicity. For instance, non-steroidal anti-inflammatory drugs (NSAIDs), certain antibiotics (like trimethoprim-sulfamethoxazole), and proton pump inhibitors (PPIs) can interfere with Methotrexate, leading to potentially severe side effects. Recognizing these methotrexate drug interactions is vital for clinicians when prescribing concomitant therapies. Similarly, patients should always inform their healthcare providers about all medications and supplements they are taking.
Beyond drug interactions, other precautions are equally important. The methotrexate dosage must be strictly adhered to, particularly the weekly administration schedule for non-oncologic indications, as overdosing can be fatal. The severe methotrexate pregnancy warning cannot be overstated; it is teratogenic and requires absolute avoidance during pregnancy and careful family planning for both partners. Understanding the detailed methotrexate side effects and contraindications is fundamental for patient safety. Whether for research or clinical application, sourcing quality Methotrexate requires an appreciation for these critical handling and safety protocols.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
