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Understanding N-(3-chloropropyl)dibutylamine: Properties, Uses, and Sourcing

For professionals in the chemical and pharmaceutical industries, a deep understanding of the properties and applications of key intermediates is essential for successful product development and manufacturing. N-(3-chloropropyl)dibutylamine (CAS: 36421-15-5) is one such compound that warrants attention due to its significant role in synthesizing important pharmaceutical agents and its presence as a related impurity.

Chemically, N-(3-chloropropyl)dibutylamine is characterized by its molecular formula C11H24ClN and a molecular weight of 205.77 g/mol. It typically appears as a light yellow to colorless liquid, with a density of approximately 0.899 g/cm³. Its boiling point is around 253.2ºC at atmospheric pressure, though it can be distilled at lower temperatures under vacuum (118-130 °C at 25 Torr). With a flash point of 106.9ºC, it requires careful handling and storage. The compound is stable when stored in a cool, dry, and well-closed container, away from moisture and direct heat or light.

The primary application of N-(3-chloropropyl)dibutylamine lies in its function as a crucial intermediate in the synthesis of Dronedarone hydrochloride, a widely used medication for treating atrial fibrillation. The specific structure of this amine chloride allows for targeted chemical reactions that build the complex Dronedarone molecule. Pharmaceutical companies looking to purchase this compound for API production rely on obtaining material with guaranteed purity, typically ≥98.0%, and low water content (≤1.0%). As a reputable manufacturer and supplier in China, we are dedicated to providing N-(3-chloropropyl)dibutylamine that meets these rigorous standards.

Beyond its synthetic utility, N-(3-chloropropyl)dibutylamine is also relevant as an impurity in the manufacturing process of Butoprozine, another antiarrhythmic drug. This highlights its importance for analytical laboratories and quality control departments that require reference standards to ensure product integrity. When seeking to procure this chemical, it is vital to consider the reputation and quality assurance practices of the manufacturer or supplier. We offer competitive price points for N-(3-chloropropyl)dibutylamine, ensuring accessibility for research and industrial applications. Our streamlined process makes it easy to obtain a quotation and place an order for your requirements.

For those in need of N-(3-chloropropyl)dibutylamine, our company stands ready to serve as a reliable source. We understand the importance of consistent quality and timely delivery in the chemical supply chain. Feel free to contact us to discuss your specific needs, inquire about bulk pricing, or request a sample. We are committed to supporting your synthesis and research endeavors with high-quality chemical intermediates.

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