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Understanding N-Boc-D-alaninol (CAS 106391-86-0): Properties and Uses

In the realm of fine chemicals, N-Boc-D-alaninol, identified by its CAS number 106391-86-0, is a compound of significant interest due to its structural attributes and wide-ranging applications. This molecule, essentially a protected form of D-alaninol, is prized for its chirality and functional groups, making it a valuable component in various chemical synthesis processes, particularly within the pharmaceutical and biochemical sectors.

Physically, N-Boc-D-alaninol typically presents as a white solid. Its melting point, commonly cited around 58-61°C, provides a key characteristic for identification and quality control. The optical activity, often expressed as [α]20/D +11° in chloroform, highlights its specific stereochemistry, a critical feature for its use in enantioselective synthesis. The molecular formula C8H17NO3 and a molecular weight of approximately 175.23 g/mol further define its chemical identity.

The significance of N-Boc-D-alaninol lies primarily in its role as a protected amino alcohol. The tert-butoxycarbonyl (Boc) group is a widely used protecting strategy for amines, offering stability during reactions involving other functional groups, such as the hydroxyl group in this case. This selective protection allows chemists to precisely control reaction pathways, making it an indispensable tool for constructing complex molecules. When researchers look to buy N-Boc-D-alaninol, they are often seeking this controlled reactivity and high enantiomeric purity.

Its applications are diverse. In pharmaceutical synthesis, it serves as a chiral building block for a variety of drug candidates and intermediates. It is also employed in the development of diagnostic reagents, where purity and specific structure are crucial. Furthermore, in the field of peptide synthesis, N-Boc-D-alaninol can be incorporated as a modified amino alcohol to introduce specific structural features or influence peptide conformation. A reliable supplier who understands these applications is key to sourcing this material.

For industries requiring this compound, identifying a reputable manufacturer who can guarantee consistent quality and competitive price for N-Boc-D-alaninol is paramount. Sourcing from established chemical hubs, such as those in China, often provides access to high-quality materials at favorable economic terms. Ultimately, understanding the properties of N-Boc-D-alaninol (CAS 106391-86-0) empowers researchers and procurement specialists to make informed decisions and drive their projects forward successfully.

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