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Understanding N-Boc-L-Alaninol: Properties and Applications for Chemists

For professionals in the chemical and pharmaceutical industries, understanding the properties and applications of key intermediates is fundamental to successful research and development. N-Boc-L-Alaninol, identified by CAS 79069-13-9, is a compound that plays a significant role in modern organic synthesis and pharmaceutical manufacturing. As a leading manufacturer and supplier in China, we aim to provide comprehensive insights into this valuable chemical building block, ensuring our clients can make informed procurement decisions.

N-Boc-L-Alaninol is characterized by its molecular formula C8H17NO3 and a molecular weight of 175.22500. It presents as a white crystalline powder, indicating a stable solid form under standard conditions. Its physical and chemical properties, such as a melting point between 59-62°C and a flash point of 121°C, are important considerations for handling and process design. Critically, it possesses a chiral center originating from L-alanine, making it an invaluable tool for stereoselective synthesis. The presence of the tert-butoxycarbonyl (Boc) protecting group on the amino function is key to its utility, shielding the amine during reactions that might otherwise affect it.

The primary application of N-Boc-L-Alaninol lies in its function as a pharmaceutical intermediate. Its protected amino alcohol structure makes it ideal for building complex molecules used in drug discovery. Specifically, it is a cornerstone in peptide synthesis, allowing for controlled addition of amino acid units. The Boc group ensures that coupling occurs regioselectively, and its subsequent removal under mild acidic conditions is a standard, efficient step in peptide chain elongation. Beyond peptides, its utility extends to the synthesis of other chiral pharmaceuticals, where precise stereochemistry is essential for efficacy and safety.

For chemists looking to buy N-Boc-L-Alaninol, understanding its role in organic synthesis beyond pharmaceuticals is also beneficial. It can be employed as a chiral auxiliary, a starting material for ligands, or in the preparation of other chiral building blocks. The free hydroxyl group offers a point for further derivatization, such as esterification, etherification, or oxidation, adding to its versatility. As a manufacturer, we focus on ensuring high purity (≥98%) and consistent quality for all these applications, recognizing that reliability is key for our clients.

We, as a N-Boc-L-Alaninol manufacturer from China, are proud to contribute to the global scientific community by providing this essential intermediate. We emphasize stringent quality control and offer competitive pricing, making it easier for research institutions and pharmaceutical companies to access the materials they need. If you are searching for a dependable supplier of N-Boc-L-Alaninol for your synthetic needs, we encourage you to reach out for detailed product specifications, samples, and quotations. Partner with us for quality and value in your chemical sourcing.

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