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Understanding N-[Fluorenylmethoxycarbonyl]-S-[[(2-phenylacetyl)amino]methyl]-L-cysteine for Drug Synthesis

In the realm of pharmaceutical chemistry, the careful selection and utilization of chemical intermediates are fundamental to the successful synthesis of active pharmaceutical ingredients (APIs). N-[Fluorenylmethoxycarbonyl]-S-[[(2-phenylacetyl)amino]methyl]-L-cysteine, identified by CAS number 159680-21-4, is one such critical compound that offers significant advantages for drug development. As a leading manufacturer and supplier of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. provides this essential building block to researchers and manufacturers worldwide.

This compound is a derivative of the amino acid cysteine, modified with two key functional groups. The N-terminal is protected by the Fmoc (9-fluorenylmethoxycarbonyl) group, a standard protecting group in peptide synthesis due to its facile removal under mild basic conditions. This selective deprotection is crucial for controlling the stepwise assembly of peptide chains. The sulfur atom in the cysteine side chain is further functionalized with a (2-phenylacetyl)amino methyl group. This sophisticated modification imbues the molecule with specific chemical characteristics that are leveraged in advanced organic synthesis.

The physical and chemical properties of N-[Fluorenylmethoxycarbonyl]-S-[[(2-phenylacetyl)amino]methyl]-L-cysteine are indicative of its utility in demanding synthetic processes. Its appearance as a white powder, with a purity typically exceeding 98%, assures researchers of its suitability for pharmaceutical applications where impurity profiles are critically scrutinized. The compound's density is recorded at approximately 1.315±0.06 g/cm³, suggesting a relatively dense solid. While precise melting and flash points may vary, its high predicted boiling point (around 782.7±60.0 °C) indicates good thermal stability, a valuable trait during reaction conditions that might involve elevated temperatures. Storing this compound in a cool, dry place in tightly sealed containers is recommended to maintain its integrity and purity.

The primary application of this intermediate lies in the pharmaceutical industry, particularly in the synthesis of complex APIs and peptides. Its structure allows for its incorporation into larger molecular frameworks, acting as a bridge or a key functional unit. For example, it can be used in the development of peptide-based drugs, where the cysteine residue plays a role in forming disulfide bonds that stabilize the peptide's tertiary structure. Pharmaceutical developers often search for 'buy CAS 159680-21-4' or 'pharmaceutical intermediate price' when seeking reliable sources. NINGBO INNO PHARMCHEM CO.,LTD. offers competitive pricing for this essential chemical, making it accessible for both research and large-scale production.

For organizations looking to purchase N-[Fluorenylmethoxycarbonyl]-S-[[(2-phenylacetyl)amino]methyl]-L-cysteine, understanding its role and sourcing from a reputable manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. is paramount. Our commitment to quality, competitive pricing, and reliable supply chain management ensures that your pharmaceutical development projects have the robust chemical foundations they require. We encourage potential clients to contact us for quotations and to learn more about how our intermediates can accelerate your research and production goals.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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