For procurement professionals and R&D teams in the pharmaceutical sector, understanding the market dynamics, including pricing and availability, of essential chemical intermediates is critical. (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine, identified by CAS number 196597-81-6, is a key intermediate in the synthesis of Ramelteon, a popular medication for insomnia. This article delves into the factors that influence the price and availability of this compound and provides guidance on how to secure a consistent supply from reliable manufacturers.

Product Overview: The Importance of Quality and Purity

(S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine is a colorless liquid with a molecular formula of C13H17NO and a molecular weight of 203.280. Its primary value lies in its high purity, typically assaying at ≥98.0%, and its specific (S) stereochemistry. These attributes are essential for its role as a precursor in the synthesis of Ramelteon, where precise molecular structure dictates pharmacological activity. When sourcing, professionals often search for '(S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine price' to compare offerings from different suppliers.

The production process for chiral intermediates can be complex, involving multiple synthesis steps and rigorous purification. This inherent complexity directly influences the manufacturing cost and, consequently, the market price of the compound. Factors such as the cost of raw materials, energy, labor, quality control, and regulatory compliance all contribute to the final price.

Factors Influencing Price and Availability

Several key elements affect the price and availability of (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine:

• Synthesis Complexity: The multi-step synthesis and the requirement for precise stereochemical control contribute significantly to production costs.
• Raw Material Costs: Fluctuations in the prices of precursor chemicals can impact the overall cost.
• Purity Requirements: Achieving and maintaining high purity (≥98.0%) necessitates advanced purification techniques, adding to the expense.
• Market Demand: The demand for Ramelteon and other potential applications directly influences the market demand for this intermediate.
• Geopolitical Factors: Supply chain disruptions, trade policies, and manufacturing location (e.g., China) can all affect availability and pricing.
• Scale of Purchase: Larger bulk orders typically command lower per-unit prices due to economies of scale in production and logistics. Procurement managers often inquire about 'bulk discounts' or 'quotations for large quantities'.

When looking to buy, professionals frequently use search terms like 'buy (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine' to identify potential suppliers and their pricing structures.

Ensuring a Reliable Supply: Partnering with Manufacturers

For consistent availability, it is advisable for companies to establish strong relationships with reputable manufacturers. As a dedicated manufacturer and supplier of pharmaceutical intermediates, we ensure a stable production pipeline for (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine. Our commitment to quality and efficiency allows us to offer competitive pricing while maintaining the high standards required for pharmaceutical applications. We understand the critical need for timely delivery and provide responsive service to our clients, whether they are in the R&D phase or scaling up for commercial production. We encourage you to contact us for the latest pricing and availability information.

Conclusion

The price and availability of (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine are influenced by a range of factors, from synthesis complexity to market demand. By understanding these dynamics and partnering with reliable manufacturers, pharmaceutical companies can secure a consistent and cost-effective supply of this vital intermediate. We are committed to being your trusted partner, providing high-quality materials to support your pharmaceutical development and manufacturing needs.