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Understanding the Properties of 4-(4-methylphenyl)piperidine (CAS 59083-39-5)

For professionals in the chemical and pharmaceutical industries, a thorough understanding of a chemical intermediate's properties is fundamental to its successful application. 4-(4-methylphenyl)piperidine, identified by CAS number 59083-39-5, is one such compound that merits detailed examination. As a key intermediate, its specific physical and chemical characteristics dictate its utility in various synthesis processes.

Chemically, 4-(4-methylphenyl)piperidine has the molecular formula C12H17N and a molecular weight of approximately 175.27 g/mol. Its structure features a piperidine ring, a saturated heterocyclic amine, attached to a para-tolyl group. This combination of an amine functionality and an aromatic moiety makes it a versatile precursor in organic synthesis. The presence of the secondary amine group allows for various reactions, such as N-alkylation, acylation, and salt formation, while the tolyl group can participate in aromatic substitution reactions or act as a structural element in more complex molecules.

Physically, the product is typically supplied as a white powder, indicating it is a solid at room temperature. While the melting point isn't explicitly stated, its appearance as a powder suggests a solid state. The boiling point is reported as 303.575 °C at 760 mmHg, a relatively high temperature, typical for organic molecules of this size and structure. Its density is listed as 1.003 g/cm³. These properties are important for handling, storage, and process design when working with this chemical intermediate.

The primary application for 4-(4-methylphenyl)piperidine is as a chemical intermediate, particularly in the synthesis of pharmaceuticals and potentially in agrochemicals or specialty materials. Its high purity (typically 97% min) ensures its suitability for demanding applications where side reactions must be minimized. R&D scientists often rely on such well-characterized intermediates to build complex molecular architectures.

For companies looking to procure this compound, understanding these properties is key to evaluating potential suppliers. When seeking to buy 4-(4-methylphenyl)piperidine, it is advisable to partner with manufacturers who provide comprehensive technical data and maintain high purity standards. Investigating manufacturers that emphasize their R&D capabilities and quality control can lead to a more reliable supply of this essential chemical intermediate.

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