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Understanding the Properties and Applications of 3-(3-Fluorophenyl)propionic Acid

For professionals in the chemical, pharmaceutical, and agrochemical industries, a deep understanding of the properties and applications of key intermediates is vital for efficient research and development. 3-(3-Fluorophenyl)propionic acid (CAS 458-45-7) is a prime example of such a compound, offering unique chemical characteristics that lend themselves to a broad spectrum of uses.

Chemically, 3-(3-Fluorophenyl)propionic acid is classified as a fluorinated organic acid. Its molecular structure, C9H9FO2, features a benzene ring substituted with a fluorine atom at the meta position and a propionic acid side chain. This combination imparts specific electronic and steric properties. The melting point typically ranges from 43-47°C, classifying it as a solid at room temperature, often appearing as a white to brown crystalline powder. Its solubility in solvents like methanol further enhances its utility in various synthetic procedures. A pKa of approximately 4.59 indicates its acidic nature, typical for carboxylic acids.

The applications of 3-(3-Fluorophenyl)propionic acid are diverse, primarily serving as a building block in organic synthesis. In the pharmaceutical sector, it is a critical intermediate for manufacturing active pharmaceutical ingredients (APIs) where the fluorine atom can enhance drug efficacy, metabolic stability, and bioavailability. Researchers actively seek this compound to develop new therapeutic agents. Similarly, in the agrochemical industry, it's used in the synthesis of pesticides, herbicides, and plant growth regulators, contributing to improved crop yields and protection.

When looking to purchase 3-(3-Fluorophenyl)propionic acid, it is essential to partner with reliable manufacturers and suppliers. Companies specializing in fine chemicals, especially those operating in China, often offer competitive pricing and high-purity grades that meet international standards such as USP, BP, and FCC. For instance, a manufacturer might offer it in 25kg drums, catering to bulk order requirements. Engaging with a supplier for price inquiries will provide clarity on the current market rates for this valuable chemical.

As a leading chemical supplier, we are committed to providing high-quality 3-(3-Fluorophenyl)propionic acid to meet the diverse needs of our clients. Whether for pharmaceutical synthesis, agrochemical development, or broader organic chemistry research, our product ensures reliability and performance. Contact us to buy this essential intermediate and discover how our manufacturing expertise can support your innovation.

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