5-Bromo-2-ethoxypyridine (CAS 55849-30-4) is a chemical compound of significant interest across various scientific disciplines, particularly in organic synthesis, pharmaceutical research, and agrochemical development. Its distinct molecular structure, characterized by a pyridine ring substituted with a bromine atom and an ethoxy group, endows it with specific chemical properties that make it a valuable intermediate. For professionals in these fields, a thorough understanding of its characteristics and applications, coupled with reliable sourcing strategies, is essential for successful project execution.
Physically, 5-Bromo-2-ethoxypyridine typically presents as a yellow solid, with a melting point in the range of 32-38°C. Its molecular formula is C7H8BrNO, and its molecular weight is approximately 202.05 g/mol. The compound's boiling point is around 216.3°C at 760 mmHg, and it has a density of approximately 1.5 g/cm³. These properties are important for handling, storage, and reaction design. Storing it in a cool, ventilated place, and ideally at temperatures between 0-8°C as suggested by some suppliers, can help maintain its stability and purity.
The primary utility of 5-Bromo-2-ethoxypyridine stems from its role as a versatile building block in organic synthesis. The bromine atom is a key reactive site, readily participating in a variety of cross-coupling reactions, such as palladium-catalyzed methods. These reactions are fundamental for constructing complex organic molecules by forming new carbon-carbon or carbon-heteroatom bonds. This makes it an ideal intermediate for synthesizing new pharmaceutical agents, agrochemicals, and other fine chemicals where precise molecular architecture is critical.
When seeking to buy 5-Bromo-2-ethoxypyridine, buyers often look for high purity, with assays of 98.0% or higher being common. This high purity is critical for ensuring the efficiency and reproducibility of synthetic processes. Manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., often offer competitive pricing and reliable quality for this intermediate. This can be advantageous for R&D departments and manufacturing facilities aiming to optimize their procurement costs without compromising on the quality of essential raw materials.
In essence, 5-Bromo-2-ethoxypyridine is a powerful tool in the synthetic chemist's arsenal. Its specific physical and chemical properties, combined with its reactivity, make it a cornerstone for innovation in key industries. By understanding these aspects and choosing suppliers that guarantee high purity and consistent supply, professionals can effectively leverage this compound to develop groundbreaking products.
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