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Understanding the Properties of Methyl 2-hydroxy-2-methoxyacetate for Synthesis

Methyl 2-hydroxy-2-methoxyacetate, bearing the CAS number 19757-97-2, is more than just a chemical name; it represents a molecule with specific attributes that are highly valued in pharmaceutical synthesis and broader organic chemistry applications. For researchers and procurement specialists, a thorough understanding of its properties is fundamental to leveraging its full potential. This article explores the key characteristics of this intermediate that make it a sought-after compound for drug development and chemical manufacturing.

At its core, Methyl 2-hydroxy-2-methoxyacetate (molecular formula C4H8O4, molecular weight 120.10) is characterized by its hydroxyl (-OH), ester (-COOCH3), and methoxy (-OCH3) functional groups. These groups offer multiple sites for chemical reactions, enabling it to serve as a versatile building block. Its appearance as a clear, colorless liquid or solid (depending on ambient temperature and precise purity, though typically described as clear and colorless) provides an immediate visual cue of its quality. Manufacturers often specify a high purity level, frequently 99%, which is critical for pharmaceutical applications where even trace impurities can disrupt reaction pathways or contaminate the final API.

Key physical properties such as density (approximately 1.174 g/cm³) and boiling point (around 128.128 °C at 760 mmHg) are also important for process engineers. These figures inform decisions regarding reaction conditions, separation techniques, and storage. The flash point, another critical safety parameter, indicates the temperature at which its vapors can ignite, guiding safe handling practices for this chemical intermediate.

When considering the purchase of Methyl 2-hydroxy-2-methoxyacetate, understanding these properties allows buyers to effectively communicate their needs to potential suppliers and ensure the material is suitable for their intended application. Whether you are looking to buy this compound for research purposes or as a bulk raw material, knowing its specifications empowers you to make informed decisions, ensuring the success of your synthetic endeavors.

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