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Understanding the Properties and Synthesis of 3-Bromo-4-fluoronitrobenzene

In the realm of fine chemicals and organic synthesis, a deep understanding of the properties and synthetic routes of key intermediates is crucial for success. 3-Bromo-4-fluoronitrobenzene, also known by its CAS number 701-45-1, is a prime example of such a compound, widely recognized for its utility in various industrial applications, particularly in the pharmaceutical and agrochemical sectors. This article aims to provide a comprehensive look at its physical and chemical characteristics, alongside the established methods for its synthesis.

Physically, 3-Bromo-4-fluoronitrobenzene typically presents as a yellow powder. Its melting point is approximately 55°C, and it possesses a boiling point of around 250.6°C at 760 mmHg. The molecular formula for this compound is C6H3BrFNO2, with a molecular weight of approximately 220 g/mol. Its structure, featuring a benzene ring with bromine, fluorine, and nitro substituents, dictates its chemical reactivity. These functional groups are key to its role as an intermediate, allowing for a variety of chemical transformations. Its solubility profile, generally slightly soluble in water but soluble in organic solvents, is also an important consideration for its handling and application in different reaction media.

The synthesis of 3-Bromo-4-fluoronitrobenzene commonly involves the bromination of 4-fluoronitrobenzene. This process typically utilizes bromine or N-bromosuccinimide as the brominating agent, often in acetic acid as a solvent under carefully controlled temperature conditions to optimize the yield and purity of the product. As a leading chemical manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. employs optimized synthesis routes to ensure the production of high-quality 3-Bromo-4-fluoronitrobenzene for global clients. Our expertise in chemical synthesis allows us to deliver a product that meets the demanding requirements of advanced chemical applications.

For businesses looking to buy this essential intermediate, understanding the quality and consistency provided by a reputable manufacturer is vital. We encourage potential customers to learn more about our capabilities and to request a quote for 3-Bromo-4-fluoronitrobenzene. By partnering with us, you secure access to a high-purity compound manufactured with rigorous quality control, supporting your research and production needs effectively. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your sourcing requirements of CAS 701-45-1.

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