Quinolinic acid (CAS 89-00-9), chemically known as pyridine-2,3-dicarboxylic acid, is a compound of significant interest in various scientific disciplines, particularly in neuroscience and synthetic chemistry. Its biological activity as an NMDA receptor agonist and its utility as a versatile chemical intermediate make it a sought-after substance for research institutions and the pharmaceutical industry. As a leading manufacturer and supplier in China, we provide high-purity Quinolinic acid to meet these critical demands.

The chemical structure of Quinolinic acid, featuring a pyridine ring substituted with two carboxylic acid groups, endows it with specific properties and reactivity. It is a colorless, crystalline solid with a notable melting point with decomposition. Biologically, it arises from the metabolism of tryptophan via the kynurenine pathway, a route also linked to the production of NAD+. This metabolic connection highlights its fundamental role in cellular biochemistry. However, its potent excitotoxic properties via NMDA receptor activation necessitate careful handling and precise application in research. For those needing to buy Quinolinic Acid for scientific studies, especially in neurobiology, understanding its precise function is key.

Synthetically, Quinolinic acid can be prepared through various oxidation methods, often starting from quinoline derivatives. The efficiency and purity achieved in these synthesis routes are crucial for its end-use applications. As a key pharmaceutical intermediate, its availability in high purity is non-negotiable. We, as a dedicated CAS 89-00-9 supplier, ensure that our production processes yield material that adheres to stringent quality specifications. This reliability is vital for clients in the pharmaceutical sector who depend on consistent intermediate quality for drug development and manufacturing.

The applications of Quinolinic acid are diverse. In neuroscience, it is an invaluable tool for studying excitotoxicity, neuronal cell death mechanisms, and the pathophysiology of neurological disorders like epilepsy, Huntington's disease, and ALS. Its ability to activate NMDA receptors allows researchers to probe these pathways in controlled experimental settings. Furthermore, its role as a pyridine-2,3-dicarboxylic acid derivative means it serves as a fundamental building block in the synthesis of various fine chemicals and complex organic molecules. For companies looking to source this compound, understanding the market and securing a dependable supply is essential. We offer competitive Quinolinic acid price points and are ready to discuss your bulk purchase requirements. Partner with us for your chemical needs and benefit from our expertise as a leading supplier.