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(R)-1-(tert-Butoxycarbonyl)-3-Hydroxypyrrolidine, identified by CAS number 109431-87-0, is a sophisticated chemical intermediate widely utilized in synthetic organic chemistry and pharmaceutical research. Understanding its physical and chemical properties is essential for researchers and procurement specialists looking to effectively incorporate it into their synthesis pathways. This molecule, often referred to as (R)-1-Boc-3-hydroxypyrrolidine, presents as a white to off-white powder, indicating a solid state at room temperature, which simplifies handling and storage compared to liquids.
The product's melting point typically ranges between 62-65°C, and it exhibits good stability under normal storage and handling conditions, particularly when kept in closed containers at room temperature or refrigerated at 0-5°C. Its solubility in common solvents like methanol further enhances its utility in various reaction setups. For chemists aiming to buy (R)-1-Boc-3-hydroxypyrrolidine, knowing these properties ensures proper experimental design and storage protocols. The chemical structure features a pyrrolidine ring substituted with a tert-butoxycarbonyl (Boc) protecting group and a hydroxyl group at the chiral center.
The primary application driving the demand for this intermediate is its role in the synthesis of pharmacologically relevant molecules. It serves as a key building block for creating ligands targeting specific biological pathways, such as the nicotinic acetylcholine receptor. Moreover, it is recognized as an important intermediate in the development of drugs like Evocalcet. Pharmaceutical companies and research institutions actively search for reliable suppliers offering this compound, often using keywords such as 'CAS 109431-87-0 specifications' or 'pharmaceutical intermediate manufacturer China'.
When procuring (R)-1-Boc-3-hydroxypyrrolidine, it's vital to consider the purity level, which is typically specified as 95% min or higher. This level of purity is critical for ensuring the success of complex multi-step syntheses and for meeting regulatory requirements in drug development. Collaborating with manufacturers known for their rigorous quality control and competitive pricing is a hallmark of effective supply chain management for R&D chemicals.
For those engaged in advanced organic synthesis or the development of new pharmaceutical agents, (R)-1-Boc-3-hydroxypyrrolidine is an indispensable chiral synthon. Exploring options to 'purchase (R)-1-Boc-3-hydroxypyrrolidine' from established Chinese manufacturers ensures access to this valuable compound at a competitive price point, facilitating smoother progression of research and development projects.
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A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
