In the intricate world of pharmaceutical manufacturing, the quality and reliability of intermediates directly dictate the success of API synthesis. 6-Chloro-5-(2-chloroethyl)oxindole, identified by its CAS number 118289-55-7, stands out as a critical building block with significant implications for drug production. Understanding its role is essential for any R&D scientist or procurement specialist involved in API development.

The Chemical Profile of 118289-55-7

Chemically known as 6-Chloro-5-(2-chloroethyl)oxindole, this compound presents as a pink to off-white solid. Its molecular formula, C10H9Cl2NO, and molecular weight of 230.09 g/mol are foundational for chemists planning synthesis reactions. The specified purity of ≥99.0% is a critical factor, as even minor impurities can lead to undesirable side reactions, reduced yields, and challenges in meeting final product specifications. Moreover, properties like low loss on drying (≤1%) indicate a stable compound, crucial for long-term storage and consistent performance during manufacturing processes. When searching for this chemical, using the CAS number '118289-55-7 supplier' can efficiently lead you to specialized manufacturers.

Key Application: A Precursor to Ziprasidone Hydrochloride

The paramount importance of 6-Chloro-5-(2-chloroethyl)oxindole lies in its role as a precursor for Ziprasidone Hydrochloride. This active pharmaceutical ingredient is a widely used atypical antipsychotic medication. The synthetic route to Ziprasidone necessitates this specific oxindole derivative to form the complex chemical structure of the drug. As such, the consistent availability of high-quality 118289-55-7 is directly linked to the affordable and stable production of Ziprasidone Hydrochloride. Pharmaceutical companies rely on manufacturers who can guarantee consistent quality and volume for this intermediate to ensure uninterrupted drug supply chains. Understanding the relationship between the intermediate and the final API is key when evaluating a potential purchase.

Strategic Sourcing for Pharmaceutical Intermediates

For procurement managers and research scientists, sourcing 118289-55-7 involves careful consideration of several factors. The price is, of course, a major consideration, especially for large-scale production. However, it should not overshadow the importance of quality and reliability. A manufacturer that can provide comprehensive documentation, such as a Certificate of Analysis (CoA) detailing purity and impurity profiles, is essential. Furthermore, a supplier with a robust production capacity and a transparent supply chain can mitigate risks associated with shortages or quality deviations. When initiating a buy inquiry, clearly state your purity requirements and expected order volume. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on providing high-grade intermediates, acting as a dependable manufacturer and supplier to support the critical needs of the pharmaceutical industry. We aim to offer competitive pricing without compromising the integrity of our products, ensuring you receive the best value for your investment in this vital chemical building block.