For chemists, researchers, and procurement specialists working with fine chemicals and pharmaceutical intermediates, a thorough understanding of product specifications is paramount. D-Phenylalanine Methyl Ester Hydrochloride, identified by its CAS number 13033-84-6, is a compound where precise specifications dictate its suitability for various synthetic applications, particularly in the pharmaceutical sector. This article aims to elucidate these key parameters, helping you make informed decisions when you need to buy this valuable intermediate.

At the forefront of specifications is the Appearance. D-Phenylalanine Methyl Ester Hydrochloride is typically described as a White Crystalline Powder. This visual characteristic is the first indicator of product quality and consistency. Deviations from this appearance might suggest impurities or issues during the manufacturing or storage process.

The Assay, or purity level, is perhaps the most critical specification for pharmaceutical applications. For D-Phenylalanine Methyl Ester Hydrochloride, an assay of ≥99.0% is commonly required. This high purity ensures that the compound will perform predictably in downstream reactions, minimizing the risk of unwanted side reactions or contamination of the final product. Researchers seeking reliable reagents for drug discovery and synthesis should always prioritize products meeting this assay standard.

Molecular Formula (C10H14ClNO2) and Molecular Weight (215.677) are fundamental identifiers that confirm the chemical identity of the substance. These values are essential for stoichiometric calculations in synthetic chemistry and for understanding the compound's physical behavior.

A crucial specification for chiral compounds is the Specific Rotation. For D-Phenylalanine Methyl Ester Hydrochloride, this value is typically specified as -32.6° to -34.6° (on a dried basis). The negative sign indicates the levorotatory nature of this D-isomer derivative, and the range signifies its enantiomeric purity. A precise specific rotation confirms that the material is indeed the desired D-enantiomer and not contaminated with its L-counterpart. This is vital for applications where stereochemistry is critical, such as in the synthesis of Nateglinide.

Other important specifications often found on a Certificate of Analysis (CoA) include Loss on Drying (≤0.5%), which indicates residual moisture content, and Heavy Metals (Pb) (≤10ppm), a measure of trace metallic impurities that are strictly regulated in pharmaceutical ingredients.

When you intend to purchase D-Phenylalanine Methyl Ester Hydrochloride, always request a detailed CoA from the manufacturer or supplier. This document will list these specifications and confirm that the batch you receive meets the required standards. Understanding these parameters empowers you to select the right product from a reputable manufacturer, ensuring successful outcomes in your research and production endeavors.