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Understanding the Specifications: Ethyl 7-bromo-1-cyclopropyl-8-(difluoromethoxy)-4-oxoquinoline

For scientists and procurement specialists in the chemical and pharmaceutical sectors, a thorough understanding of product specifications is crucial. Ethyl 7-bromo-1-cyclopropyl-8-(difluoromethoxy)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 194805-07-7) is a prime example of a complex intermediate where detailed specifications define its suitability for advanced synthesis projects.

The molecular structure itself, C₁₆H₁₄BrF₂NO₄, with a molecular weight of approximately 402.19 g/mol, provides the fundamental identity. However, its utility is further defined by precise analytical data. High purity, often exceeding 98% or 99%, is a standard requirement for pharmaceutical intermediates. This purity is typically validated through techniques such as High-Performance Liquid Chromatography (HPLC), which separates and quantifies impurities, and Nuclear Magnetic Resonance (NMR) spectroscopy (¹H NMR and ¹⁹F NMR), used to confirm the presence and position of all structural elements, including the characteristic signals from the cyclopropyl and difluoromethoxy groups.

When searching for this compound, terms like 'CAS 194805-07-7 purity' or 'ethyl 7-bromo-1-cyclopropyl-8-(difluoromethoxy)-4-oxo-1,4-dihydroquinoline-3-carboxylate specifications' are common. These searches indicate a need for detailed technical information that assures researchers of the material's quality. Reputable suppliers will provide Certificates of Analysis (CoA) detailing the results of these analytical tests, alongside crucial physical properties such as appearance (typically a white powder) and melting point range.

Manufacturers specializing in fine chemicals and pharmaceutical intermediates invest significantly in analytical capabilities to ensure their products meet global standards. For anyone looking to buy this intermediate, requesting and reviewing the CoA is a standard practice. This due diligence ensures that the purchased material aligns with the intended application, whether it's for early-stage research or large-scale production, guaranteeing the integrity and reproducibility of experimental outcomes.

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