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Understanding the Specifications of 1-(Pyridin-2-yl)piperazine (CAS 34803-66-2)

For professionals in the chemical and pharmaceutical sectors, understanding the precise specifications of critical intermediates is fundamental to successful research and development. 1-(Pyridin-2-yl)piperazine (CAS: 34803-66-2) is no exception. As a versatile building block, its performance in synthesis relies heavily on its purity, physical characteristics, and stability. This article delves into the key specifications that R&D scientists and procurement managers should scrutinize when looking to buy this compound.

The purity of 1-(Pyridin-2-yl)piperazine is often the most critical specification. Most reputable manufacturers will guarantee a minimum purity, commonly cited as 95%min or higher. This is essential for ensuring predictable reaction outcomes and avoiding unwanted byproducts, particularly in sensitive pharmaceutical synthesis. When you engage with a supplier, always request a Certificate of Analysis (CoA) that clearly details the purity level, along with analytical methods used for determination (e.g., GC, HPLC).

Beyond purity, the physical appearance of 1-(Pyridin-2-yl)piperazine is also an important indicator. It is typically described as a clear, colorless to yellow liquid. Deviations from this appearance might suggest contamination or degradation, warranting further investigation. Other physical properties, such as boiling point (e.g., 120-122 °C at 2 mm Hg) and density (around 1.072 g/mL at 25 °C), provide additional data points for quality assurance and process optimization. These parameters are crucial for formulators and process engineers when considering the purchase of this chemical.

Stability and storage conditions are also vital specifications. 1-(Pyridin-2-yl)piperazine is generally stable at room temperature in closed containers. However, understanding its incompatibilities (e.g., strong oxidizing agents, acids) is crucial for safe handling and storage. Partnering with a knowledgeable manufacturer means gaining access to expert advice on optimal storage protocols, ensuring the longevity and integrity of the product. For anyone looking to acquire this compound, choosing a reliable supplier in China that adheres to these exacting standards is key to successful projects.

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